DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk21 and ppk25

DIOPT Version :9

Sequence 1:	NP_651704.2	Gene:	ppk21 / 43485	FlyBaseID:	FBgn0039675	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_995766.1	Gene:	ppk25 / 2768722	FlyBaseID:	FBgn0053349	Length:	451	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	124/514 - (24%)
Similarity:	187/514 - (36%)	Gaps:	139/514 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 YLKDYAAESSVHGIRYLADPKMRNYLN--IRVIWLLILLTTSIGAIVVYVDLNELYQTVRIQTTI 109
            :|.:...|||:||:.|:|    |..|:  .|:.|..|:|.::..||...  ||:.|:........
  Fly    13 WLAELCQESSIHGMPYIA----RRDLHWAERLFWTFIILGSAYYAISSC--LNQWYRFRDNPIVY 71

  Fly   110 KNTMLPIFRI-PFPSIGLCPRNRLNWKILETE---AVDHFLGANVSAAQKD--LFVKFFTAAGDP 168
            :...|...|| ||..|.||||..     .|||   .::...|.:.|..::.  .:.||..|....
  Fly    72 EYEYLFGLRIFPFVGITLCPRYH-----DETEIPRLINQTWGVDPSEDKEKAVYYRKFLLAINGL 131

  Fly   169 HLSRLNEMSNFFGNKTLTDELHMLDHLDLREVYKFIQFR--------------CQDLFHTCRWRG 219
            ..|.|..:.. |.|.|..|.::.|:.| |....|.|..:              ||......|: |
  Fly   132 RYSTLETLEP-FENDTTLDNVNYLNIL-LTLQKKVIAVKIPPELAPIITEVGLCQTSSQLNRY-G 193

  Fly   220 NPVNCCEVIEYQ-FTEAGLCFVFNTEISPASRQKAR--------EDKYYP--LRTPHYG----EG 269
            ||....|..:.: ..:.|......|.:.|.:...|.        |:...|  :|||.:.    |.
  Fly   194 NPYGKLETQDMEPMKQCGYLSNCITSLKPINSIVAPIFMYLHDVEEMMLPDDMRTPSFDAKDIES 258

  Fly   270 SGLDLFLRLNRSFIRPGKRGINVMIKQPQQWSDVVRHVPHEAHTRISITPRFTVTDERTRTVTPE 334
            ..||:.|                                   ||        |..:...|.:...
  Fly   259 KDLDIML-----------------------------------HT--------TSAESEVRNLPVA 280

  Fly   335 IRRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKCSPSIFFPISDKDNFTACKASDF 399
            .|:|.|.||.:..:|.     .|....||..|..:..|:||.|.|  :|.::..: ...|..|..
  Fly   281 YRKCRFSDENNLQYYS-----PYHPSLCRLECRIKWALSLCNCKP--YFYVAAPE-VPICTVSGM 337

  Fly   400 KCLYDNRFTFSIERHPEEDDFVKNPFKESMICDCFTSCSQLVFD--RVFTTTTLDNNETDTEAGT 462
            .||..:::   :||.                |||:.||.:..|.  :|...|..|:|.:...
  Fly   338 LCLARSKW---LERP----------------CDCYPSCREETFTIFKVSDQTGGDDNYSGER--- 380

  Fly   463 MRLDIFYQSGWFIQYQ-----TNMRFTFV--ELLASFGGIIGLFLGASLLSAFELAYYF 514
                  ::....|..|     .|.|..|.  :|:.||||.||||||||.::.:.:.|:|
  Fly   381 ------FERTLIINLQISRMGINRRVVFSTDQLIMSFGGAIGLFLGASFMTIYGVVYFF 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	121/507 (24%)
ppk25	NP_995766.1	ASC	18..432	CDD:279230	121/506 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7253
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.870