Protein Alignment ppk21 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_651704.2
• Gene: ppk21 / 43485
• FlyBaseID: FBgn0039675
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 110/608 - (18%)
• Similarity: 188/608 - (30%)
• Gaps: 193/608 - (31%)

  Fly    51 YAAESSVHGIRYL--ADPKMRNYLNIRVIWLLILLTTSIGAIVVYVDLNELYQTVRIQTTIKNTM 113
            |...::.||.:.:  ..||.      :.:|.|:   |.:.|.:|........||........:..
  Rat    29 YCNNTNTHGPKRIICEGPKK------KAMWFLL---TLLFACLVCWQWGVFIQTYLSWEVSVSLS 84

  Fly   114 LPIFRIPFPSIGLCPRNRLNWKILETEAVDHFLGANVSAAQKDLFVKFFTAAGD----PHLSRLN 174
            :....:.||::.:|     |....:...|.|.|        |||: |...|..|    |..|..|
  Rat    85 MGFKTMNFPAVTVC-----NSSPFQYSKVKHLL--------KDLY-KLMEAVLDKILAPKSSHTN 135

  Fly   175 EMS--------------------------NFFG----------------------------NKTL 185
            ..|                          |.||                            |.|:
  Rat   136 TTSTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTV 200

  Fly   186 ------------TDELHMLDHLDLREVYKFIQFRCQDL----------FHTCRWRGNPVNCCEVI 228
                        ..|.::|...::     |.|...|||          ...|.:...|.:.....
  Rat   201 CTFRNFTSATQAVTEWYILQATNI-----FSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFT 260

  Fly   229 EYQFTEAGLCFVFNTEISPASRQKAREDKYYPLR----------TPHYGEGSGLDLFLRLNRS-- 281
            ...:.:.|.|::||..::..:...|.....:.|:          .|.....:|..|.|...|:
  Rat   261 PIFYPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYP 325

  Fly   282 FIRPGKRGINVMIKQPQQWSDVVRHVPHEAHTRISITPRFTVTDERTRTVTPEIRRCIF-GDEVD 345
            |||  :.||..|                 |.|..||.........:....:|    |.. |.:|.
  Rat   326 FIR--EEGIYAM-----------------AGTETSIGVLLDKLQGKGEPYSP----CTMNGSDVA 367

  Fly   346 NPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKCSPSIF-FPISDKDNFTACKASDFKCLYDNRFTF 409
            ..:..:..:..|.:..|...|.|:|:::.|.|...:: .|..:|    .|...||.   |..:.:
  Rat   368 IQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEK----YCNNRDFP---DWAYCY 425

  Fly   410 -SIERHPEEDDFVKNPFKESMICDCFTSCSQLVFDRVFTTTTLD--------------------- 452
             |::....:        :|:.:..|..||:...:.  .|.:..|
  Rat   426 LSLQMSVVQ--------RETCLSMCKESCNDTQYK--MTISMADWPSEASEDWILHVLSQERDQS 480

  Fly   453 NNETDTEAGTMRLDIFYQSGWFIQYQTNMRFTFVELLASFGGIIGLFLGASLLSAFELA------ 511
            :|.|.:..|.::|:|::|...:...:.:.....|.||::.||..|.::|.|:|...|..
  Rat   481 SNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDF 545

  Fly   512 -YYFSIGLYLYIHGKRKLRKPEP 533
             :...|.|.....|.|:.|...|
  Rat   546 IWITVIKLVASCKGLRRRRPQRP 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	104/586 (18%)
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	110/608 (18%)
		deg-1	29..538	CDD:273309	103/576 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820