DRSC/TRiP Functional Genomics Resources

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Protein Alignment ppk21 and asic-1

DIOPT Version :9

Sequence 1:NP_651704.2 Gene:ppk21 / 43485 FlyBaseID:FBgn0039675 Length:550 Species:Drosophila melanogaster
Sequence 2:NP_491214.3 Gene:asic-1 / 191422 WormBaseID:WBGene00022815 Length:823 Species:Caenorhabditis elegans


Alignment Length:449 Identity:80/449 - (17%)
Similarity:149/449 - (33%) Gaps:145/449 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   156 DLFVKFF----TAAGDPHLSRLNEMSNFFG-----------NKTLTDELHMLDHLDLREVYKFIQ 205
            |..|||:    :....|.:.:..|....:|           .|.:.:.:..:|.|...|.:| |.
 Worm   421 DRVVKFWDIQPSTTMSPIVKKKEERDKAYGYTGVKDRIALRAKAMENMIFAVDALTEEEKWK-IS 484

  Fly   206 FRCQDLFHTCRWRGNPVNC-CEVIEYQFTEAGLCFVFNTEISPASRQKAREDKYYPLRTPHYG-- 267
            :...|....|.:.|...|. .:.:||.....|.||.:..::...:.:::         .|.||  
 Worm   485 YNKSDFIMKCSFNGRECNVKHDFVEYLDPTYGACFTYGQKLGNNTNERS---------GPAYGLR 540

  Fly   268 --------------EGSGLDLFLRLNRSFIRPGKRGINV--------------MIKQPQQWSDVV 304
                          |.:|:.|.:........|...|.:.              |::.|..:.|.|
 Worm   541 LEVFVNVTEYLPTTEAAGVRLTVHATDEQPFPDTLGFSAPTGFVSSFGIKLKSMVRLPAPYGDCV 605

  Fly   305 RHVPHEAHTRISITPRFTVTDERTRTVTPEIRRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQE 369
            |.         ..|..|..|.:                             .|....|:..|.|:
 Worm   606 RE---------GKTEDFIYTQK-----------------------------AYNTEGCQRSCIQK 632

  Fly   370 HVLNLCKCSPSIFFPISDKDNFTACKASDFKCLYDNRFTFSIERHPEEDDFVKNPF------KES 428
            |:...|.|....|.|..:..|   |...|                |.:.:.:||..      .:.
 Worm   633 HLSKTCGCGDPRFPPYRESKN---CPVDD----------------PYKRECIKNEMHVATRDSKK 678

  Fly   429 MICDCFTSCSQLVFDRVFTTTTLDNNETD-----------------TEAGTMRLDIFYQSGWFIQ 476
            :.|.|...|:|.|:...::.:.......|                 .|.|:| ::::::.   :.
 Worm   679 LGCSCKQPCNQDVYSVSYSASRWPAIAGDLSGCPLGMAAHHCLNYKREQGSM-IEVYFEQ---LN 739

  Fly   477 YQTNMR---FTFVELLASFGGIIGLFLGASLLSAFELA-YYFSIGLYLYIHGKRKLRKP 531
            |::.:.   :.:..||:.|||.:||::|.|:::..|:| ::|.:.:.| |...|..|:|
 Worm   740 YESLLESEAYGWSNLLSDFGGQLGLWMGVSVITIGEVACFFFEVFISL-ISSNRTKRRP 797

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ppk21NP_651704.2 ASC 51..513 CDD:279230 74/429 (17%)
asic-1NP_491214.3 deg-1 16..779 CDD:273309 74/428 (17%)
ASC 17..>104 CDD:279230
ASC <469..788 CDD:295594 68/390 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D303969at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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