Protein Alignment ppk21 and asic-2

DIOPT Version :10

• Sequence 1: NP_651704.2
• Gene: ppk21 / 43485
• FlyBaseID: FBgn0039675
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 112/566 - (19%)
• Similarity: 204/566 - (36%)
• Gaps: 151/566 - (26%)

  Fly    49 KDYAAESSVHGIRYLADPKMRNYLNIRVIWLLI-LLTTSIGAIVVYVDLNELYQTVRIQTTIKNT 112
            ||::..|:|..:.::|:  ..|.:: |:.|:.| |....:.|..:|:.:.:.:.   ...|: ||
 Worm    11 KDFSNWSTVAVVPHVAN--ANNKIS-RIFWIAIFLFVLGMFAYELYILIAKFFS---YPATV-NT 68

  Fly   113 MLPIFRIPFPSIGLCPRNRLNWKILETEAVDHFLGAN-VSAAQKDLFVKFFTAAGDPHLSRLNEM 176
            .:...:..||.:.:|..|...:.::::.:.  |...| :.....|..|..|:
 Worm    69 EILFEKQIFPVVTVCNMNPYKYSVVKSNSA--FSSVNTLMTTYSDATVGTFS------------- 118

  Fly   177 SNFFGNKTLTDELHMLDH-------------LDLREVYKFIQFRCQDLFHTCRWRGNPVNCCEVI 228
            ::.:|.....||.:.||.             .|..:|.....:  .||...|.:.|.|.:
 Worm   119 TDKWGLYADNDETYDLDSRAADALVLEANLISDTAKVPALYTY--ADLIQDCSFAGIPCS----- 176

  Fly   229 EYQFTE-----AGLCFVFNTEISPASRQKAREDKYYPLRTPHYGEGSGLDLFLRLNRSFIR---- 284
            |..||:     .|.|:.||.:.| .:...:||           |...||.|.|.:.::...
 Worm   177 ESDFTKFIDPVYGACYSFNEDAS-LNYSVSRE-----------GIQFGLKLMLTVTQTKTNGNTD 229

  Fly   285 -------PGKR-GINVMIKQPQQWSD-VVRHVPHEAHTRISITPRFTVTDERTRTVTPEIRRCIF 340
                   .|.| |:|.....|...|: :...|.:|:...:|:|       :..|...| ...|:.
 Worm   230 SLPTTKLAGARIGVNSRGSSPGLDSNGIDAGVGYESAVSVSLT-------QNVRAKKP-YGTCVD 286

  Fly   341 GDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKC-SPSIFFPISDKDNFTACK--ASDFKCL 402
            .:...:.:||   ||.|.:..|.:.|.|...:..|:| :|.:....:|    |||:  .:|..||
 Worm   287 REPDSSDYYK---DFIYTLETCFNGCKQRDTIAKCQCANPRLALGSTD----TACQPIKADLDCL 344

  Fly   403 Y---DNRFTFSIERHPEEDDFVKNPFKESMICDCFTSCSQLVFDRVFTTTTLDNNE----TDTEA 460
            .   .|:.:.:    |..|..|:        |:|...|.:..:....:.....:..    |.:.|
 Worm   345 QTLKGNQTSST----PNIDLLVE--------CNCNPPCDESTYTPTVSLAQFPSTSYYVATSSTA 397

  Fly   461 GT------------------------MRLDIFYQSGWFIQYQTNMRFTFVELLASFGGIIGLFLG 501
            |.                        |.:.:|.::..:..|.....:|...::...||..||:||
 Worm   398 GVGSCSSTNSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGYTVSNVINDLGGQAGLWLG 462

  Fly   502 ASLLSAFELAYYFSIGLYLYIHGKRKLRKPEPGVLTIQFGQRKITP 547
            .|::|..|:.     ||.|.:           |...:..|..|:.|
 Worm   463 LSVISVVEMT-----GLMLVM-----------GAFCVTGGAIKMAP 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:459966	103/528 (20%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	104/534 (19%)