DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk21 and degt-1

DIOPT Version :9

Sequence 1:	NP_651704.2	Gene:	ppk21 / 43485	FlyBaseID:	FBgn0039675	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_505703.3	Gene:	degt-1 / 184921	WormBaseID:	WBGene00009109	Length:	852	Species:	Caenorhabditis elegans

Alignment Length:	453	Identity:	96/453 - (21%)
Similarity:	157/453 - (34%)	Gaps:	128/453 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LPYLKDYAAESSVHGIRYLADPKMRNYLNIRVIWLLILLTTSIGAIVVYVDLNELYQTVRIQT-- 107
            :|.|..:|.::|:.|.|||   ..|.....||:|         |.:||:......||.....|
Worm    38 IPALDRFAEDTSMLGFRYL---HTRYKTWFRVLW---------GFVVVFFIGLTFYQVFERVTYY 90

  Fly   108 TIKNTM--------LPIFRIPFPSIGLCPRNRLNWKILETEAVDHFLGANVSAAQKDLFVKFFTA 164
            .|||.:        ||  .:.||:||:|  |::..|           .::|::...||....
Worm    91 FIKNPLTTRRSYETLP--NMYFPTIGVC--NKMQIK-----------ASSVASKNPDLLRGM--- 137

  Fly   165 AGDPHLSRLNEMSNFFGNKTLTDELHMLDHLDLREVYKFIQFRCQDLFHTCRWRGNPVNCCEVIE 229
                 .|.|:|.|:   |.:..|||...|.:|:..:|:.......|||.:|.: |...:|.:.|.
Worm   138 -----CSVLDESSS---NSSRFDELDKFDDVDILSLYRNSFQSADDLFVSCEF-GKSGSCQDEIR 193

  Fly   230 YQFTEAGLCFVFNTEISPASRQKAREDKYYPLRTPHYGEGSGLDLFLRLNRSFIRPG---KRGIN 291
            ..:|..|||:    .:||..          .:..|  |..:.|.|.|.|....|.||   :.|:.
Worm   194 PIYTPFGLCY----SVSPNK----------TILRP--GPETTLSLVLNLEVHEIIPGTVVEPGVV 242

  Fly   292 VMIKQPQQWSDVVRHVPHEAHTRISITPRFTVTDERTRTVT---PEIRRC-IFGDEVDNPHYKNF 352
            :.|   ...:..:.|.....|.            |..:.||   .|:|:. :......:...::|
Worm   243 LSI---YDGASSLSHYSEGIHL------------EAGKVVTIPVNEVRKLRLHESSCGSTKMESF 292

  Fly   353 PDFEYWVGNCRSRCHQEHVLNLCKCSP-------SIFFPISD-----------------KDNFTA 393
            .:.||....|......:.:...|.|.|       .:|...:|                 |.|...
Worm   293 SEKEYSKAACEWSVSVKQIEKECGCIPIRNPIYRGVFDNKNDPLNNSTEIPKKKYKKWKKRNIPR 357

  Fly   394 CK-ASDFKCLYDNRFTFSIERHPEEDDFVKNPFKESMICDCFTSCSQLVFDRVFTTTTLDNNE 455
            |. ..:.:|:.:     .:...|..||.:           |...|..:.|..:.....|.::|
Worm   358 CTLRQEIECVQE-----KLNIRPHIDDSI-----------CPDDCDDISFSSIVFGGKLSSSE 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	94/447 (21%)
degt-1	NP_505703.3	ASC	44..>318	CDD:279230	78/343 (23%)
degt-1	NP_505703.3	ASC	<704..836	CDD:295594
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810