Protein Alignment ppk21 and mec-10

DIOPT Version :10

• Sequence 1: NP_651704.2
• Gene: ppk21 / 43485
• FlyBaseID: FBgn0039675
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_509438.1
• Gene: mec-10 / 181101
• WormBaseID: WBGene00003174
• Length: 724
• Species: Caenorhabditis elegans
• Alignment Length: 681
• Identity: 125/681 - (18%)
• Similarity: 218/681 - (32%)
• Gaps: 246/681 - (36%)

  Fly    41 WHFMLPYLKDYAAESSVHGIRYLADPKMRNYLNIRVIWLLILLTTSIGAIVVYVDLNELYQTVRI 105
            ||     |:.:..::|.|||..|.......|   |..|:.:||..:|..|...|.:.:.||.:
 Worm    95 WH-----LQQFCYKTSSHGIPMLGQAPNSLY---RAAWVFLLLICAIQFINQAVAVIQKYQKM-- 149

  Fly   106 QTTIKNTMLPIFRIPFPSIGLCPRNRLNWKILET-EAVDHFLGANVS------------------ 151
             ..|.:..|.....|||:|.||..|.....::.: :::...||...|
 Worm   150 -DKITDIQLKFDTAPFPAITLCNLNPYKDSVIRSHDSISKILGVFKSVMKKAGDSSSEALEEEEE 213

  Fly   152 ------------------AAQKDLFVKFFTA--------------------AGD----------- 167
                              |.:|..|....:|                    :||
 Worm   214 TEYDMNGITIQAKRKKRGAGEKGTFEPANSACECDEEDGSNECEERSTEKPSGDNDMCICAFDRQ 278

  Fly   168 ---------------------------------------------------------PHLSRLNE 175
                                                                     .|.:.:..
 Worm   279 TNDAWPCHRKEQWTNTTCQTCDEHYLCSKKAKKGTKRSELKKEPCICESKGLFCIKHEHAAMVLN 343

  Fly   176 MSNFFGNK-----------------TLTDELHMLDHLD---------LREVYKFIQFRCQ-DLFH 213
            :..:||:.                 .:|||:.::....         |.|..:.:..:.: :|.|
 Worm   344 LWEYFGDSEDFSEISTEEREALGFGNMTDEVAIVTKAKENIIFAMSALSEEQRILMSQAKHNLIH 408

  Fly   214 TCRWRGNPVNCCEVIEYQF-----TEAGLCFVFN--TEISPASRQKAREDKYYPLRTPHYGEGSG 271
            .|.:.|.|   |: |:..|     ...|.|||||  .||..:|.:..          |.|    |
 Worm   409 KCSFNGKP---CD-IDQDFELVADPTFGNCFVFNHDREIFKSSVRAG----------PQY----G 455

  Fly   272 LDLFLRLNRSFIRPGKRGINVMI----KQPQQWSDVVRHVPHEAHTRISITPRFTVTDERTRTVT 332
            |.:.|.:|.|...|....:.:.:    |....:.|...:.....:.. |...|.   .:.:|...
 Worm   456 LRVMLFVNASDYLPTSEAVGIRLTIHDKDDFPFPDTFGYSAPTGYIS-SFGMRM---KKMSRLPA 516

  Fly   333 PEIRRCIFGDEVDNPHYKN--FPDFEYWVGNCRSRCHQEHVLNLCKCSPSIFFPISDKDNFTACK 395
            |      :||.|::....|  :..:.|....|...|.||.:::.|.||...|..|..........
 Worm   517 P------YGDCVEDGATSNYIYKGYAYSTEGCYRTCFQELIIDRCGCSDPRFPSIGGVQPCQVFN 575

  Fly   396 ASDFKCLYDNRFTFSIERHPEEDDFVKNPFKESMICDCFTSCSQLVF-----DRVFTTTTL---- 451
            .:..:||         |:|..:...:...||    |.|...|:|.::     :.::.:..|
 Worm   576 KNHRECL---------EKHTHQIGEIHGSFK----CRCQQPCNQTIYTTSYSEAIWPSQALNISL 627

  Fly   452 --------DNNETDTEAGTMRLDIFYQSGWFIQYQTNMRFTFVELLASFGGIIGLFLGASLLS-- 506
                    :.||...|...| |::||::..|.....:..:..|:::|.|||.:||:.|.|:::
 Worm   628 GQCEKEAEECNEEYKENAAM-LEVFYEALNFEVLSESEAYGIVKMMADFGGHLGLWSGVSVMTCC 691

  Fly   507 -----AFELAYYFSIGLYLYIHGKRKLRKPE 532
                 |||| .|.:|..::   .::::|:.|
 Worm   692 EFVCLAFEL-IYMAIAHHI---NQQRIRRRE 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:459966	118/650 (18%)
mec-10	NP_509438.1	deg-1	99..696	CDD:273309	114/644 (18%)