Protein Alignment ppk21 and unc-105

DIOPT Version :10

• Sequence 1: NP_651704.2
• Gene: ppk21 / 43485
• FlyBaseID: FBgn0039675
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001364812.1
• Gene: unc-105 / 174306
• WormBaseID: WBGene00006832
• Length: 974
• Species: Caenorhabditis elegans
• Alignment Length: 719
• Identity: 131/719 - (18%)
• Similarity: 219/719 - (30%)
• Gaps: 265/719 - (36%)

  Fly    29 RDARKNSRLGKLWHFMLPYLKDYAAESSVHGIRY--LADPKMR-NYLNIRVIWLLILLTTSIGAI 90
            |:.|.|..|.  |:.:   .|.:..:|:.|||.:  .||.|.| .:.....|.||.||......|
 Worm   103 RNIRMNGHLD--WNQL---RKSFEKQSTFHGISHAATADGKWRWFWYTAFTICLLALLIQIFFLI 162

  Fly    91 VVYVDLNELYQTVRIQTTIKNTMLPIFRIPFPSIGLCPRNRLNWKILET--------EAVDHFLG 147
            ..|   .:..:||.:....:|.       |||||.:|..|......:::        ||....:|
 Worm   163 SKY---RQYGKTVDLDLKFENA-------PFPSITICNLNPYKKSAIQSNPNTKAMMEAYSRRIG 217

  Fly   148 A-----NVSAAQKDLFVKFFTAAGDPHLSRLNEMSNFFGNKTLTD------------ELHMLD-- 193
            :     .::||        .:|.|..|...........|...|.|            ::..|.
 Worm   218 SGDKTEGIAAA--------LSATGGLHAKVRRAKRKAKGKPRLRDRRYHQAFAQCLCDIEQLTGD 274

  Fly   194 -------------HLDLREVYKFIQFR-----CQ-DLFHTCRWRGNPVN------CCEVIE---- 229
                         .:|......|:...     || |......|...|.:      |.|.::
 Worm   275 RKGSCFAAFKGKIEIDTNNTAGFMNLHTSRCLCQLDTVSKALWPCFPYSSWKEKLCSECVDNTGH 339

  Fly   230 -----YQFTE--------AGLCFV---FN-----------TEISP-------------ASR---- 250
                 |:..|        ..||..   :|           .||||             ||:
 Worm   340 CPMRFYKGNELYENIKEQVDLCLCHKEYNHCVSTRDDGIILEISPNDELNDLDIGKKIASQLSAQ 404

  Fly   251 ----------------------------------------------QKAREDKYYPLR------- 262
                                                          :||:|...|.|.
 Worm   405 QEKQAEVTTTEAPTVTQALGFEELTDDIAITSQAQENLMFAVGEMSEKAKESMSYELDELVLKCS 469

  Fly   263 ------------TPHYGEGSGLDLFLRLNRSFIRPGKR-----GINVMIKQPQQWSDVVRHVP-- 308
                        |.||....|.......||:......|     |:.|::     :::|..::|
 Worm   470 FNQKDCQMDRDFTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLL-----YANVSEYLPTT 529

  Fly   309 ---------HEAHTRISITP---------------RFTVTDERTRTVTPEIRRCIFGDEVDNPHY 349
                     |:.|    |.|               .|.|..::...:.|....|..|.| |...:
 Worm   530 EAVGFRITVHDKH----IVPFPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGE-DAATF 589

  Fly   350 KNFPDFEYWVGNCRSRCHQEHVLNLCKCSPSIFFPISDK--DNFTACKASDF---KCLYDNRFTF 409
            . :..|:|.|..|...|.|:.::..|.|:..: :|:::.  :|...|:|.:.   :||.:.....
 Worm   590 V-YTGFQYSVEACHRSCAQKVIVEACGCADPM-YPVAEMFGNNTKPCQAVNMDQRECLRNTTLWL 652

  Fly   410 SIERHPEEDDFVKNPFKESMICDCF--TSCSQLVFDRVFTTTTLDNNETDT-------------- 458
            .       :.:.|.  ||::|.||:  ..|.:..::..:::....:.....
 Worm   653 G-------ELYSKG--KEAIIPDCYCHQPCQETNYEVTYSSARWPSGSAKVMECLPGDFLCLEKY 708

  Fly   459 EAGTMRLDIFYQSGWFIQYQTNMRFTFVELLASFGGIIGLFLGASLLSAFELAYYFSIGLYLYIH 523
            ......:.|||:...:...|.:..:|...:||..||:.||::|||::|..|:..........|:.
 Worm   709 RKNAAMVQIFYEELNYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLIVFATQAYVR 773

  Fly   524 GKRK 527
             |||
 Worm   774 -KRK 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:459966	121/681 (18%)
unc-105	NP_001364812.1	deg-1	119..763	CDD:273309	121/682 (18%)