Protein Alignment ppk21 and Asic2

DIOPT Version :9

• Sequence 1: NP_651704.2
• Gene: ppk21 / 43485
• FlyBaseID: FBgn0039675
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_006532059.1
• Gene: Asic2 / 11418
• MGIID: 1100867
• Length: 596
• Species: Mus musculus
• Alignment Length: 615
• Identity: 126/615 - (20%)
• Similarity: 218/615 - (35%)
• Gaps: 187/615 - (30%)

  Fly     4 PLELPRARRPLYRDYGGKSGLIQTQRDARKNSRLGKLWHFMLPYLKDYAAESSVHGIRYLADPKM 68
            |..:..||:|    .|.:||..:.|...  .:|.|:      |.|    :.:.:||:|::...:.
Mouse    29 PAAVAAARQP----GGDRSGDRELQGPG--VARRGR------PSL----SRTKLHGLRHMCAGRT 77

  Fly    69 R--NYLNIRVIWLLILLTTSIGAIVVYVDLNELY-----QTVRIQTTIKNTMLPIFRIPFPSIGL 126
            .  .....|.:|:| ...||:|.::.:.....||     ...|:......      ::|||::.:
Mouse    78 AAGGSFQRRALWVL-AFCTSLGLLLSWSSNRLLYWLSFPSHTRVHREWSR------QLPFPAVTV 135

  Fly   127 CPRNRLNWKIL---ETEAVDHFLGANVSAAQKDLFVKFFTAAGDPHLSRLNEMSNFFGNKTLTDE 188
            |..|.|.:..|   :.....|:||..:........|.......:|......::::|   :.....
Mouse   136 CNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQWFRKLADF---RLFLPP 197

  Fly   189 LH-------MLDHLDLREVYKFIQFRCQDLFHTCRWRG--------NPVNC-------------- 224
            .|       .:|.|.         .:.:|:..:|::||        :.|:|
Mouse   198 RHFEGISAAFMDRLG---------HQLEDMLLSCKYRGELCGPHNFSSVSCPPREPALSDPALPR 253

  Fly   225 -CEVIEYQ---------FTEAGLCFVFNTEISPASRQKAREDKYYPLRTPHYGEGSGLDLFLRLN 279
             .|.:.:.         ||:.|.|::||          :.||....|.|...|.|:||::.|.:.
Mouse   254 SPEALRWAPGTGHQAPVFTKYGKCYMFN----------SGEDGKPLLTTVKGGTGNGLEIMLDIQ 308

  Fly   280 RSFIRP---------GKRGINVMIKQPQQWSDVVRHVPHEAHTRISITP---RFTVTDERTRTVT 332
            :....|         .:.|:.|.|....:       .|........:.|   .|..|.|:..|..
Mouse   309 QDEYLPIWGETEETTFEAGVKVQIHSQSE-------PPFIQELGFGVAPGFQTFVATQEQRLTYL 366

  Fly   333 P----EIRRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKC---------------- 377
            |    |.|....|.:.       ||  .|.:..||..|...:::..|.|
Mouse   367 PPPWGECRSSEMGLDF-------FP--VYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQ 422

  Fly   378 -----SPSIFFPISDKD-NFTACKASDFKCLYDNRFTFSIERHPEEDDFVKNPFKESMICDCFTS 436
                 .|::.. :::|| |:..|:.   .|        ::.|:.:|...||.|.|        ||
Mouse   423 HKECAEPALGL-LAEKDSNYCLCRT---PC--------NLTRYNKELSMVKIPSK--------TS 467

  Fly   437 CSQLVFDRVFTTTTLDNNETDTEAGTMRLDIFYQSGWFIQYQT---NMRFTFVELLASFGGIIGL 498
            ...|  ::.|     :.:|.......:.||||:::   :.|:|   ...:....||...||.:||
Mouse   468 AKYL--EKKF-----NKSEKYISENILVLDIFFEA---LNYETIEQKKAYEVAALLGDIGGQMGL 522

  Fly   499 FLGASLLSAFELAYYFSIGLYLYIHGKRKL 528
            |:|||:|:..||   |.   |:|...|.||
Mouse   523 FIGASILTILEL---FD---YIYELIKEKL 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:279230	108/551 (20%)
Asic2	XP_006532059.1	ASC	64..590	CDD:383197	114/564 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920