Protein Alignment ppk21 and asic4

DIOPT Version :10

• Sequence 1: NP_651704.2
• Gene: ppk21 / 43485
• FlyBaseID: FBgn0039675
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_031749131.1
• Gene: asic4 / 100486325
• XenbaseID: XB-GENE-940165
• Length: 535
• Species: Xenopus tropicalis
• Alignment Length: 562
• Identity: 117/562 - (20%)
• Similarity: 192/562 - (34%)
• Gaps: 171/562 - (30%)

  Fly    48 LKDYAAESSVHGIRYLADPKMRNYLNIR-VIWLLILLTTSIGAIVVYVDLNELYQTVR------- 104
            |..:|:.|::||:|::.   ....|.|: .:|.|..|.:.         |..|||..:
 Frog    41 LAAFASTSTLHGLRHIF---QTGRLGIKQSLWALAFLASL---------LFFLYQVAKCALYYLE 93

  Fly   105 ------IQTTIKNTMLPIFRIPFPSIGLCPRNRLNWKILETEAVDHFLGANVSAAQKDLFVKFFT 163
                  :...:...|:      ||:|.:|..||..                            .:
 Frog    94 HPHVTAVDEEVMGEMI------FPAITICNINRFR----------------------------HS 124

  Fly   164 AAGDPHLSRLNEMSNFFGNKTLTDELH-----MLDHLDLREVYKFIQFRCQDLFHTCRWRGNPVN 223
            |..||.:..|   :|..|......|.|     |.|..|:.::......:..::..:|.:.|   :
 Frog   125 ALTDPDIYHL---ANLTGLPPKDREGHRDSDLMYDDPDMLDIVNRTGHQLAEMLKSCNFSG---D 183

  Fly   224 CCEVIEYQ--FTEAGLCFVFNTEISPASRQKAREDKYYPLRTPHYGEGSGLDLFLRLNRSFIRPG 286
            .|....:.  ||..|.|:.||.            ||.:|..:...|.|:||::.|.:.:....|.
 Frog   184 SCSAQNFSVVFTRYGKCYTFNA------------DKKHPKVSRQGGMGNGLEIMLDIQQEEYLPI 236

  Fly   287 KR---------GINVMIKQPQQWSDVVRHVPHEAHTRISITP---RFTVTDERTRTVTPE----I 335
            .|         ||.|.|....:       .|:.......::|   .|....|:..|..|:    .
 Frog   237 WRETNETSFEAGIRVQIHSQDE-------PPYIHQMGFGVSPGFQTFVSCQEQRMTYLPQPWGNC 294

  Fly   336 RRCIFGDEVDNPHYKNFPDFEYWVGNCRSRCHQEHVLNLCKCSPSIFFPISDKDNFTACKASDFK 400
            |..|.|:|..:.:      ..|.:..||.:|.:|.|:..|.|. .:..|    .|.|.|....:.
 Frog   295 RSSIPGEEFLSGY------STYSISACRLQCEKEAVIRKCACR-MVHMP----GNETICSPVMYM 348

  Fly   401 C---LYDNRFTFSIERHPEEDDFVKNPFKESMICDCFTSCSQLVFDRVFTTTTLDN--------- 453
            |   :.||....:.|:                 |.|.|.|:...:.:..:...:.|
 Frog   349 CADHILDNMVEDTSEK-----------------CSCPTPCNLTRYSKEISMVRIPNKGSARYLAR 396

  Fly   454 ----NETDTEAGTMRLDIFYQSGWFIQYQT---NMRFTFVELLASFGGIIGLFLGASLLSAFELA 511
                |||......:.||||:::   :.|:|   ...:....||...||.:|||:|||.|:..|:.
 Frog   397 KYNKNETYIRENFLVLDIFFEA---LNYETIEQKKAYDLPSLLGDIGGQMGLFIGASFLTILEIL 458

  Fly   512 YYFSIGLYLYIHGKRK---------LRKPEPGVLTIQFGQRK 544
            .|    :|..|..|.|         .:||...:.|:.....|
 Frog   459 DY----MYEVIRDKVKRVAGRKQSPAKKPSENIATLVMDDNK 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk21	NP_651704.2	ASC	51..513	CDD:459966	107/517 (21%)
asic4	XP_031749131.1	ENaC	39..514	CDD:273304	117/562 (21%)