Protein Alignment Dop1R2 and adrb3b

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_073770286.1
• Gene: adrb3b / 792519
• ZFINID: ZDB-GENE-081022-154
• Length: 415
• Species: Danio rerio
• Alignment Length: 514
• Identity: 157/514 - (30%)
• Similarity: 214/514 - (41%)
• Gaps: 157/514 - (30%)

  Fly    90 TTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVAD 154
            |||..|:..:.|..||         |.|..|.||.||.|||||:.|...|||.||.||.|:|.||
Zfish     5 TTTLIPEDVKPLLVLP---------LALVIFLTVIGNLLVILAIARTPLLHTTTNVFIISMAFAD 60

  Fly   155 CLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPM 219
            .::|.||.|. .|..|:...|..|...||:|.||||...||||..||.|:::||.|||.|..:.:
Zfish    61 LIMGCVVQPL-GLSMVVAGKWVLGNPMCDLWTSLDVFCVTASIETLCAIAVERYIAITRPLEHQV 124

  Fly   220 RMTVKRAAGLIAAVWICSSAISFPAIV------WWRAARDGEMPAYKCTFTEHLGYLVFSSTISF 278
            .:..:|||.::..|||.||.:||..|:      .:.||.|....:..|.|..:..|.:|||.:||
Zfish   125 LLGKRRAAYIVCTVWIVSSLVSFVPIMNHNSRANYLAANDCYNNSECCDFHTNQHYAIFSSVVSF 189

  Fly   279 YLPLLVMVFTYCRIYRAAVIQTRSLK-IGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGG 342
            |:|||||||.|.:::   .|..:.|| ||..::...|
Zfish   190 YVPLLVMVFLYGKVF---AIANKQLKLIGKDRLRFLS---------------------------- 223

  Fly   343 GGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNFSLSRK 407
                                           |..|:..:.|      .|.||        |.||:
Zfish   224 -------------------------------SCNEDSCEIP------EGSAR--------SYSRR 243

  Fly   408 LAK-FAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNP 471
            ..| ..||.||.|||||:||:|.:||||||:.|::..|..|.  ..::|..::.|||:.||.:||
Zfish   244 TTKHVVKEHKALKTLGIIMGIFSLCWLPFFIFNIIKSFNPEV--PTQLVFLLLNWLGYANSGLNP 306

  Fly   472 VIYACWSRDFRRAFVRLLCMCCPRKIRRKYQPTMRSKSQCHVAAAMVAASTSFGYHSVNQIDRTL 536
            :|| |.|.::|.||..||                                   |.......::|.
Zfish   307 IIY-CHSPEYRNAFFNLL-----------------------------------GCKKPKHFNQTT 335

  Fly   537 MXRQLSSCSTC-------------------SGGSNCGGSRS------AHHQHHSSGTAT 570
            :.:.|.|.::|                   .||:.|....|      ...|.|:..|.|
Zfish   336 VNKHLQSFTSCIQSNSSVRMDCMGHKDPIARGGNTCSDMSSVLKGEEVEIQPHNDSTMT 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	130/370 (35%)
		TM helix 2	143..169	CDD:320195	13/25 (52%)
		TM helix 3	182..212	CDD:320195	17/29 (59%)
		TM helix 4	224..246	CDD:320195	10/21 (48%)
		TM helix 5	266..295	CDD:320195	15/28 (54%)
		TM helix 6	297..442	CDD:320195	35/146 (24%)
		TM helix 7	453..478	CDD:320195	11/24 (46%)
adrb3b	XP_073770286.1	None