Protein Alignment Dop1R2 and htr7c

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_002662019.5
• Gene: htr7c / 572143
• ZFINID: ZDB-GENE-060526-5
• Length: 400
• Species: Danio rerio
• Alignment Length: 459
• Identity: 149/459 - (32%)
• Similarity: 226/459 - (49%)
• Gaps: 77/459 - (16%)

  Fly    46 YNISEDVYFYFNGLPTSTELVLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVG 110
            :|.|.| :|.|.....::| |||. :|.....:|.||.....|         .:.|:....:::.
Zfish     3 FNSSLD-FFSFTHPEVASE-VLNG-SSHFFYNISMAMWNKSCG---------EQLLDFTAAEKIV 55

  Fly   111 LLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTW 175
            :...|.:.:..||.||.||::||...:.|...:||.:.||||||..|.:|||||..:.::....|
Zfish    56 IGLMLAIITTVTVIGNMLVVIAVCVVKKLRQPSNYLLVSLAVADLSVAIVVMPFVIVTDLTGGKW 120

  Fly   176 FFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAI 240
            .||..:|:|:..:||:..||||:.|||||:|||..||.|.:||.|...:..|.:|..||:.|::|
Zfish   121 LFGEVFCNIFIGMDVMCCTASIMTLCVISVDRYLGITRPLTYPARQNGQLMAKMIFGVWLVSASI 185

  Fly   241 SFPAIVWWRAARDGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKI 305
            :.|....|  |::.. .|..|..::..||.::|:.::||:|::||:|.|.:|::||      .|.
Zfish   186 TLPPFCGW--AKNVN-TAGVCLISQDFGYTIYSTAVAFYIPMIVMLFMYYKIFKAA------RKS 241

  Fly   306 GTKQVLMASGELQLT--LRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHG 368
            |.|.        :.|  .|..|..|...:..::.|              |...|
Zfish   242 GAKH--------RFTDFSRRERLETVASEALRMQG--------------LKPQH----------- 273

  Fly   369 GGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWL 433
               |....||  ...||.|    |:|.|   :|.|:      |.:|:|||.|||:::|||.||||
Zfish   274 ---TPGVAEE--CAALSRL----LSRER---QNISI------FKREQKAATTLGVIVGVFGICWL 320

  Fly   434 PFFVVNLLSGF-C-IECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRK 496
            |||:::....| | ::|......:...:.|.|:.||.|||.|||.::||.|..: |.|..|..|.
Zfish   321 PFFILSTARPFICGVKCSCIPIWLERTLLWFGYANSLMNPFIYAFFNRDLRSTY-RDLLRCRYRN 384

  Fly   497 IRRK 500
            |.|:
Zfish   385 INRR 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	127/366 (35%)
		TM helix 2	143..169	CDD:320195	14/25 (56%)
		TM helix 3	182..212	CDD:320195	16/29 (55%)
		TM helix 4	224..246	CDD:320195	7/21 (33%)
		TM helix 5	266..295	CDD:320195	11/28 (39%)
		TM helix 6	297..442	CDD:320195	39/146 (27%)
		TM helix 7	453..478	CDD:320195	10/24 (42%)
htr7c	XP_002662019.5	7tmA_5-HT7	54..374	CDD:320452	128/379 (34%)
		TM helix 1	55..81	CDD:320452	9/25 (36%)
		TM helix 2	88..114	CDD:320452	14/25 (56%)
		TM helix 3	127..157	CDD:320452	16/29 (55%)
		TM helix 4	169..191	CDD:320452	7/21 (33%)
		TM helix 5	208..237	CDD:320452	11/28 (39%)
		TM helix 6	299..329	CDD:320452	17/29 (59%)
		TM helix 7	342..367	CDD:320452	10/24 (42%)