Protein Alignment Dop1R2 and si:dkey-247m21.3

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_017208337.2
• Gene: si:dkey-247m21.3 / 559089
• ZFINID: ZDB-GENE-091204-249
• Length: 390
• Species: Danio rerio
• Alignment Length: 438
• Identity: 134/438 - (30%)
• Similarity: 194/438 - (44%)
• Gaps: 117/438 - (26%)

  Fly   108 RVGLLAFLFLFSFATVFGNSLVILAVIRERYLH-TATNYFITSLAVADCLVGLVVMPFSALYEVL 171
            |:.|...|......|..||.||::|:.::|.|. ..||:||.|||.||.||.|||||.:|: |:.
Zfish    22 RITLSIVLVTIIIMTALGNLLVMVALCKDRQLRKKKTNFFIVSLAFADLLVALVVMPLAAI-ELT 85

  Fly   172 ENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAI-TDPFSYPMRMTVKRAAGLIAAVWI 235
            ...|.:|..:|.:..|||||.:|||||:||.|:||||:|| ..|..|..:||..|.:.::...|:
Zfish    86 TGKWNYGETFCLVRTSLDVLLTTASILHLCCIALDRYYAICCQPLVYNNKMTPVRVSLMLVGCWV 150

  Fly   236 CSSAISF-PAIVWW--------------RAARDGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVM 285
            ....||| |.:..|              .::|:.     .|.|..:..|.:..|.::||:||::|
Zfish   151 IPFFISFLPIMQSWNTIGIESFIEQRKLNSSRNS-----TCVFMVNQPYALVCSAVAFYVPLVLM 210

  Fly   286 VFTYCRIYRAAVIQTRSLKIGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGG 350
            |..|.|||..|:...|  :||:               :||.|:
Zfish   211 VLAYQRIYVTAMGHAR--RIGS---------------LHRAGS---------------------- 236

  Fly   351 GSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEK 415
                                ..|||....|....|.:.|                        |.
Zfish   237 --------------------APTSTYPNNDQHGSSRIKN------------------------ET 257

  Fly   416 KAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRD 480
            ||||||.::||.|.:||.||||.|::..|....:..:...:.:  |||:|||.:||.:||..:|.
Zfish   258 KAAKTLAVIMGCFCLCWAPFFVTNVVDPFINYSVPWQMWTAWL--WLGYINSGLNPFLYAFLNRA 320

  Fly   481 FRRAFVRLLCMCCPRKIRRK--YQPTMRSKSQC--HVAAAMVAASTSF 524
            |||||:.:|| |...:..|:  :.|:    .||  .|....::...||
Zfish   321 FRRAFLMILC-CGDERYARQGGFSPS----RQCSESVNGTSISLRLSF 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	119/379 (31%)
		TM helix 2	143..169	CDD:320195	17/25 (68%)
		TM helix 3	182..212	CDD:320195	20/30 (67%)
		TM helix 4	224..246	CDD:320195	6/22 (27%)
		TM helix 5	266..295	CDD:320195	12/28 (43%)
		TM helix 6	297..442	CDD:320195	29/144 (20%)
		TM helix 7	453..478	CDD:320195	10/24 (42%)
si:dkey-247m21.3	XP_017208337.2	7tmA_5-HT4	23..325	CDD:320184	121/392 (31%)
		TM helix 1	24..50	CDD:320184	8/25 (32%)
		TM helix 2	58..84	CDD:320184	17/26 (65%)
		TM helix 3	96..126	CDD:320184	19/29 (66%)
		TM helix 4	139..162	CDD:320184	6/22 (27%)
		TM helix 5	191..220	CDD:320184	12/28 (43%)
		TM helix 6	254..284	CDD:320184	18/53 (34%)
		TM helix 7	293..318	CDD:320184	10/26 (38%)