Protein Alignment Dop1R2 and CG13579

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Alignment Length: 745
• Identity: 163/745 - (21%)
• Similarity: 251/745 - (33%)
• Gaps: 213/745 - (28%)

  Fly    97 LSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVILAVIRER---YLHTATNYFITSLAVADCLVG 158
            ::|.:||:         .:.:.:...:..|.|||..:...|   |:|....|.:||||:.|..:|
  Fly    35 IAETIEAV---------LILVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLTSLALNDLTIG 90

  Fly   159 LVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTV 223
            |::.|| .|...|.:.|.:|..:|.|...|....|..|.:.|..:::|||.....|..|....:.
  Fly    91 LLITPF-GLMPALFHCWPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSK 154

  Fly   224 KRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYKC-TFTEHLGYLVFSSTISFYLPLLVMVF 287
            |....:::..||.|..: |..:|..:...........| .|.....|.:. ||.:.|.| ..||.
  Fly   155 KGCVAILSLTWIISLTV-FGFLVLPKGYYFNNTGLMACEPFYSKPSYRIL-STCALYFP-TTMVL 216

  Fly   288 TYCRIYRAAVIQTR-SLKIGTKQVLMA----------SGELQLTLRIHRGGTTRDQQNQVSGGGG 341
            .||  |.::...:| .|...|..:..|          :...||.:..|:      |.:|.:
  Fly   217 MYC--YGSSFHMSRFRLNDPTMPLTAAAHHPHPHPHPTAAQQLQMHQHQ------QHHQQA---- 269

  Fly   342 GGGGGGGGGGSLSHSHSH-----SHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKN 401
                  |....|.|.|||     ||.:|.||.|......|  |....||...:.|||...:|..
  Fly   270 ------GMHSHLYHGHSHHPSHPSHPNHPNHHGHPHHHGP--PVMGHLSMAMSMGLAGMPNMTN- 325

  Fly   402 FSLSRKLAKFAKEKKAAKT----LGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSA----- 457
             .:::|:....::..:..|    ..|.:| ||:...|:.:              :|||:|
  Fly   326 -KITKKIVPIQEKNSSGSTSRSMAAISLG-FIVMVTPWTI--------------QEIVTACTGSK 374

  Fly   458 -------IVTWLGWINSCMNPVIYACWSRDFRRAFVRLL-CMCCPRKIRRKYQPTMRSKSQ-CHV 513
                   :|||....||..||.:|...:.||||...:|: ..|.|      ::.|...||. ||:
  Fly   375 LPPFLDFLVTWTALSNSLWNPFMYWLLNSDFRRMSRQLMPNKCFP------HEDTPEHKSGCCHI 433

  Fly   514 AAAMVAASTSFGYHSVNQIDRTLM--------XRQLSSCSTCSGGSNCGGSRSAHHQHHSSGTAT 570
            .|              |..:.|.:        .|.........||.:.||.        |||...
  Fly   434 NA--------------NDFEITTLPIPPEPPSSRPPGGAGGGGGGPSSGGP--------SSGGGV 476

  Fly   571 PSSSQRS----CTRCQSFHRHHHRSRRRSSGMQMRGDYNSTTAVNSALAKTIVTISAPPVAAASA 631
            .||...|    |.|.::      .|..||:...:||...
  Fly   477 ASSIGGSVLGICGRSRT------NSLSRSASQYIRGTMG-------------------------- 509

  Fly   632 SSLHLGVGGRPSSVSTLTIASVPPTLSGSGS-----------PGGSVSGATTPLAPSL---KALT 682
                   ||..:..:|.|.::..|.:.|...           ..|:::.....|.|.|   ..|.
  Fly   510 -------GGVHNHQATETFSTTRPDIEGLSEKYWGEILERTVSSGNLNAMQKHLPPHLPYAHHLV 567

  Fly   683 PGPSNSSGHH----VSFMPMTGMK-RLRSSNASLGSPNGIIST-------------------VAG 723
            ........||    .||...:.:: .|..|.|:..:..|..|.                   .|.
  Fly   568 HQIHQPQQHHQQQTTSFSKASDLQLNLNLSQAATAAELGKFSNSEPKLCEHLFHDVNCAKSKAAN 632

  Fly   724 ADTTSAPSL--------IDASEDQVQMRNQ 745
            .|..|:..|        | .:||.:..:||
  Fly   633 GDGESSGKLACGRSIPDIXYAEDVILAKNQ 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	102/398 (26%)
		TM helix 2	143..169	CDD:320195	11/25 (44%)
		TM helix 3	182..212	CDD:320195	9/29 (31%)
		TM helix 4	224..246	CDD:320195	5/21 (24%)
		TM helix 5	266..295	CDD:320195	10/28 (36%)
		TM helix 6	297..442	CDD:320195	36/164 (22%)
		TM helix 7	453..478	CDD:320195	12/36 (33%)
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	50/193 (26%)
		TM helix 1	41..65	CDD:410626	5/32 (16%)
		TM helix 2	75..101	CDD:410626	11/26 (42%)
		TM helix 3	113..143	CDD:410626	9/29 (31%)
		TM helix 4	156..175	CDD:410626	4/19 (21%)
		TM helix 5	200..220	CDD:410626	9/23 (39%)
		7tm_GPCRs	<334..407	CDD:475119	20/87 (23%)
		TM helix 6	340..366	CDD:410628	6/40 (15%)
		TM helix 7	377..402	CDD:410628	8/24 (33%)