DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dop1R2 and HTR1F

DIOPT Version :9

Sequence 1:NP_001263072.1 Gene:Dop1R2 / 43484 FlyBaseID:FBgn0266137 Length:807 Species:Drosophila melanogaster
Sequence 2:NP_000857.1 Gene:HTR1F / 3355 HGNCID:5292 Length:366 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dop1R2NP_001263072.1 7tm_4 123..>295 CDD:304433
7tm_1 125..474 CDD:278431
HTR1FNP_000857.1 7tmA_5-HT1F 24..359 CDD:320456
TM helix 1 26..50 CDD:320456
TM helix 2 59..81 CDD:320456
TM helix 3 97..119 CDD:320456
Agonist binding. /evidence=ECO:0000250 99..108
DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250 120..122
TM helix 4 142..158 CDD:320456
TM helix 5 179..202 CDD:320456
TM helix 6 292..314 CDD:320456
Agonist binding. /evidence=ECO:0000250 306..310
TM helix 7 326..351 CDD:320456
NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 343..347
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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