Protein Alignment Dop1R2 and HTR1D

DIOPT Version :9

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: NP_000855.1
• Gene: HTR1D / 3352
• HGNCID: 5289
• Length: 377
• Species: Homo sapiens
• Identity: / - (0%)
• Similarity: / - (0%)
• Gaps: / - (0%)

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tm_4	123..>295	CDD:304433
		7tm_1	125..474	CDD:278431
HTR1D	NP_000855.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		7tmA_5-HT1B_1D	35..367	CDD:320455
		TM helix 1	40..66	CDD:320455
		TM helix 2	73..99	CDD:320455
		TM helix 3	111..141	CDD:320455
		Agonist binding. /evidence=ECO:0000250	114..123
		DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250	135..137
		TM helix 4	153..176	CDD:320455
		TM helix 5	194..223	CDD:320455
		TM helix 6	294..324	CDD:320455
		Agonist binding. /evidence=ECO:0000250	314..318
		TM helix 7	335..360	CDD:320455
		NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250	352..356

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910