Sequence 1: | NP_001263072.1 | Gene: | Dop1R2 / 43484 | FlyBaseID: | FBgn0266137 | Length: | 807 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_000854.1 | Gene: | HTR1B / 3351 | HGNCID: | 5287 | Length: | 390 | Species: | Homo sapiens |
Alignment Length: | 425 | Identity: | 146/425 - (34%) |
---|---|---|---|
Similarity: | 209/425 - (49%) | Gaps: | 69/425 - (16%) |
- Green bases have known domain annotations that are detailed below.
Fly 87 GGGTTTPEPDLSEFLEALPND-----------------RVGLLAFLFLFSFATVFGNSLVILAVI 134
Fly 135 RERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILN 199
Fly 200 LCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYKCTF- 263
Fly 264 TEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMASGELQLTLRIHRGGT 328
Fly 329 TRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNGLA 393
Fly 394 RHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAI 458
Fly 459 VTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCC 493 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Dop1R2 | NP_001263072.1 | 7tm_4 | 123..>295 | CDD:304433 | 81/172 (47%) |
7tm_1 | 125..474 | CDD:278431 | 126/349 (36%) | ||
HTR1B | NP_000854.1 | 7tmA_5-HT1B_1D | 46..380 | CDD:320455 | 136/380 (36%) |
TM helix 1 | 51..77 | CDD:320455 | 9/25 (36%) | ||
TM helix 2 | 84..110 | CDD:320455 | 14/25 (56%) | ||
TM helix 3 | 122..152 | CDD:320455 | 20/29 (69%) | ||
Agonist binding | 125..134 | 3/8 (38%) | |||
DRY motif, important for ligand-induced conformation changes and signaling | 146..148 | 1/1 (100%) | |||
TM helix 4 | 164..187 | CDD:320455 | 12/22 (55%) | ||
TM helix 5 | 205..234 | CDD:320455 | 12/32 (38%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 259..281 | 6/50 (12%) | |||
TM helix 6 | 307..337 | CDD:320455 | 19/29 (66%) | ||
Agonist binding | 327..331 | 3/3 (100%) | |||
TM helix 7 | 348..373 | CDD:320455 | 10/24 (42%) | ||
NPxxY motif, important for ligand-induced conformation changes and signaling | 365..369 | 2/3 (67%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |