Protein Alignment Dop1R2 and Octalpha2R

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_061501849.1
• Gene: Octalpha2R / 3289716
• VectorBaseID: AGAMI1_006243
• Length: 636
• Species: Anopheles gambiae
• Alignment Length: 633
• Identity: 170/633 - (26%)
• Similarity: 248/633 - (39%)
• Gaps: 198/633 - (31%)

  Fly    47 NISEDVYFYF---NGLPTSTELVLNATTSATSATLSPAMVATGG----GGTTT---PEPDLSEFL 101
            ||:::.:...   ||.......:.|.:.:..:|..:.|..|.||    |||..   |..:|:...
Mosquito    10 NITQEDFLAIVGANGTVGGGPTMFNDSLAVAAAAAAAAAAAAGGVAGPGGTAAGVGPGENLTILH 74

  Fly   102 EALPNDRVGLLAFLFLFS-------FATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGL 159
            .|.|:...  |..:.:.|       ...|.||.|||:|:..|:.|....|:||.||||||..:||
Mosquito    75 GAYPSGYT--LPHIIIASIIVTILMIVIVVGNMLVIIAIATEKTLKNIQNWFIASLAVADFFLGL 137

  Fly   160 VVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVK 224
            |:||||...|:: ..|.||..|||:..::|||..|:||:|||:|||||||:||....|....|..
Mosquito   138 VIMPFSLANELM-GYWIFGNWWCDVHSAMDVLLCTSSIMNLCLISLDRYWSITKAIEYLKSRTPA 201

  Fly   225 RAAGLIAAVWICSSAISFPAIVWWRAAR-DGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFT 288
            |||.:||||||.|:.:..|.::.|:|.| :|.:...:|..::.:||:::|:..|||:|..:|||.
Mosquito   202 RAAFMIAAVWIMSALVCIPPLLGWKAQRPEGHVELPQCQLSQDIGYVLYSALGSFYIPSCIMVFV 266

  Fly   289 YCRIYRAAVIQTRSLKIGTKQVLMASGELQLTLRIHRGGT--------------------TRDQQ 333
            |.|||.||..:.|.   |.::..:.....|.|......||                    ...||
Mosquito   267 YIRIYFAAKARARR---GIRKKPLKPPSEQDTSFTRNAGTVPMPSLPSASSNNNQSAAAAAHHQQ 328

  Fly   334 NQVSGGGGGGGGGG------------------------GGGGSLSHSHSHSHHHH---------- 364
            :.|....|..|||.                        ....|.|.:.:.....|
Mosquito   329 HPVQLSSGAQGGGSTQIATIEPPPRGTPMPIPVVTCDFASDMSTSEAATAEQDQHGPISPVALEP 393

  Fly   365 -------------HNHGGGTTTSTPEEPDDEPLSA------------------------------ 386
                         .:..|.|......||...|.||
Mosquito   394 KDTLKVTQPAQQGRSTNGITAAGAATEPVASPSSAAARSRALSVGIDTDMVSEFDPSSSDSGVIS 458

  Fly   387 ---------------LHNNGLARHR------------HMGKNFSLS------------------- 405
                           :...|.|:.|            |.|:..:.:
Mosquito   459 RCAVVKPLKFRLCQPIFGKGKAKARQANAKAAGHGGAHAGRGNAPNCTQPMLAAPGGQQAISQLI 523

  Fly   406 -----------------------------RKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLL 441
                                         |::|: .|||:|...||::||.||.||||||.:.:|
Mosquito   524 AAKQTDSACSELEPALPPKPKPRDPEKEKRRIAR-KKEKRATLILGLIMGSFIACWLPFFFLYIL 587

  Fly   442 SGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLL 489
            ...|.:|...:...| :..|||::||.:||.||..:::||||||.|:|
Mosquito   588 VPVCPDCHIPDSAFS-LAFWLGYMNSALNPAIYTIFNKDFRRAFRRIL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	147/535 (27%)
		TM helix 2	143..169	CDD:320195	16/25 (64%)
		TM helix 3	182..212	CDD:320195	18/29 (62%)
		TM helix 4	224..246	CDD:320195	11/21 (52%)
		TM helix 5	266..295	CDD:320195	14/28 (50%)
		TM helix 6	297..442	CDD:320195	46/316 (15%)
		TM helix 7	453..478	CDD:320195	10/24 (42%)
Octalpha2R	XP_061501849.1	None