Protein Alignment Dop1R2 and octr-1

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: NP_001024569.1
• Gene: octr-1 / 184469
• WormBaseID: WBGene00006411
• Length: 408
• Species: Caenorhabditis elegans
• Alignment Length: 437
• Identity: 141/437 - (32%)
• Similarity: 199/437 - (45%)
• Gaps: 97/437 - (22%)

  Fly   113 AFLFLFSFATV-----FGNSLVILAVIRERYLH-TATNYFITSLAVADCLVGLVVMPFSALYEVL 171
            |.|.:.|..||     |||.||::.|.|:|.|. ...|:.|.||||||.||||:|||.:..||::
 Worm    21 AVLTISSMLTVMLLIIFGNLLVVVTVYRDRKLRMQRQNWLIVSLAVADMLVGLLVMPLTLTYEIV 85

  Fly   172 ENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWIC 236
             ..|..|...|:||.:|||||.|||||::|.||||||:::|.|.:||...|..|....|...||.
 Worm    86 -GEWTMGNILCEIWLALDVLFVTASILHICAISLDRYFSVTSPLTYPATRTPLRMFIYIGVSWIV 149

  Fly   237 SSAISFPAIVWWRAAR-DGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQT 300
            |..|..|.|..||..| :||     |:.:..|||:::||..|||:|:::::..|.:||...:..:
 Worm   150 SLLICLPPIFGWRPERAEGE-----CSVSTDLGYVLYSSLGSFYIPVVILIIVYAKIYSITIRHS 209

  Fly   301 RSLKIGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHH 365
            |       |.|..:.....||.:.   |.|...|:                    .::..:....
 Worm   210 R-------QRLKETERRDHTLNML---TIRSSTNE--------------------RYNMEYELEE 244

  Fly   366 NHGGGTTTSTPEEPDDE--------------------------------PLSALHNNGLA---RH 395
            |       |.|.|.:.|                                .|...||:..|   ..
 Worm   245 N-------SDPIEDEKEKVVTNRDMINKVCWQLRKISEELPRQGVKVSIALDTNHNSPPASDLTR 302

  Fly   396 RHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHE--EIVSAI 458
            :...|.|...||....|||::|...|||::..||:.|||||::.::..|     .||  .:|...
 Worm   303 KLEEKKFCEKRKRKLKAKERQATLLLGIILSAFILSWLPFFLIYVIGAF-----GHEAPPLVFKF 362

  Fly   459 VTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRKIRRKYQPTM 505
            ..|||:.||.:|||||..::|:|:|...:.|     .|..|...|.|
 Worm   363 FFWLGYCNSGINPVIYTVFNREFKRGLCKQL-----HKFERFIHPLM 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	133/406 (33%)
		TM helix 2	143..169	CDD:320195	15/25 (60%)
		TM helix 3	182..212	CDD:320195	20/29 (69%)
		TM helix 4	224..246	CDD:320195	7/21 (33%)
		TM helix 5	266..295	CDD:320195	12/28 (43%)
		TM helix 6	297..442	CDD:320195	35/179 (20%)
		TM helix 7	453..478	CDD:320195	11/24 (46%)
octr-1	NP_001024569.1	7tmA_alpha2_AR	22..389	CDD:320187	135/414 (33%)
		TM helix 1	23..49	CDD:320187	10/25 (40%)
		TM helix 2	57..83	CDD:320187	15/25 (60%)
		TM helix 3	95..125	CDD:320187	20/29 (69%)
		TM helix 4	137..160	CDD:320187	8/22 (36%)
		TM helix 5	175..204	CDD:320187	12/28 (43%)
		TM helix 6	319..349	CDD:320187	14/29 (48%)
		TM helix 7	357..382	CDD:320187	11/24 (46%)