Protein Alignment Dop1R2 and ser-2

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: NP_001024339.1
• Gene: ser-2 / 182110
• WormBaseID: WBGene00004777
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 482
• Identity: 150/482 - (31%)
• Similarity: 226/482 - (46%)
• Gaps: 94/482 - (19%)

  Fly    66 VLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVI 130
            |:||:::.::.||.|..:..    |:...|.:...:|.:    :|.:.:|.:.:. ||.||:||:
 Worm    24 VINASSAVSTTTLPPLDIPM----TSMKPPSIIPTVELV----LGTITYLVIIAM-TVVGNTLVV 79

  Fly   131 LAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTA 195
            :||...|.|....|||:.|||.:|..|.:.|||...:..:....|..|...|..:.:.|:|..|:
 Worm    80 VAVFSYRPLKKVQNYFLVSLAASDLAVAIFVMPLHVVTFLAGGKWLLGVTVCQFFTTADILLCTS 144

  Fly   196 SILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYK 260
            ||||||.|:|||||||.:|.:|..:.|.|....:|..|||.|..||.|.|:.|...::..|.. .
 Worm   145 SILNLCAIALDRYWAIHNPINYAQKRTTKFVCIVIVIVWILSMLISVPPIIGWNNWQENMMED-S 208

  Fly   261 CTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIY-------------------------------- 293
            |..:....::|||:..||:|||||||..|.:|:
 Worm   209 CGLSTEKAFVVFSAAGSFFLPLLVMVVVYVKIFISARQRIRTNRGRSALMRIQNAEGDDDYRKMS 273

  Fly   294 --RAAVIQTR-SLKIGTK-QVLMASGELQL-TLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSL 353
              ||:|...| |.::|.| .:::|.|:..: ||..|                      ...||||
 Worm   274 IKRASVESARTSSRVGEKTPLVIADGQTTVTTLAAH----------------------STDGGSL 316

  Fly   354 SHSHSHSHHHHHNHGGGTTTSTPEEPDDE----PLSALHNNGLARHRHMGKNFSLSRKLAKFAKE 414
            ....:..|..:||: |.......:..:||    |.:.|.                .|:....|||
 Worm   317 PKDETTKHMKYHNN-GSCKVKVKDVKEDEGNPNPTAVLR----------------KREKISVAKE 364

  Fly   415 KKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSR 479
            |:||||:.:::.||..|||||||..::..||..|..|.::..|. ||||:|||.:||.:|...:.
 Worm   365 KRAAKTIAVIIFVFSFCWLPFFVAYVIRPFCETCKLHAKVEQAF-TWLGYINSSLNPFLYGILNL 428

  Fly   480 DFRRAFVRLLC---MCCPRKIRRKYQP 503
            :|||||.::||   :...|:.|...||
 Worm   429 EFRRAFKKILCPKAVLEQRRRRMSAQP 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	131/403 (33%)
		TM helix 2	143..169	CDD:320195	11/25 (44%)
		TM helix 3	182..212	CDD:320195	17/29 (59%)
		TM helix 4	224..246	CDD:320195	9/21 (43%)
		TM helix 5	266..295	CDD:320195	14/62 (23%)
		TM helix 6	297..442	CDD:320195	40/151 (26%)
		TM helix 7	453..478	CDD:320195	11/24 (46%)
ser-2	NP_001024339.1	7tmA_tyramine_octopamine_R-like	58..434	CDD:320188	133/421 (32%)
		TM helix 1	59..85	CDD:320188	10/26 (38%)
		TM helix 2	92..118	CDD:320188	11/25 (44%)
		TM helix 3	131..161	CDD:320188	17/29 (59%)
		TM helix 4	173..196	CDD:320188	10/22 (45%)
		TM helix 5	214..243	CDD:320188	14/28 (50%)
		TM helix 6	362..392	CDD:320188	17/29 (59%)
		TM helix 7	402..427	CDD:320188	11/25 (44%)