Protein Alignment Dop1R2 and ser-7

DIOPT Version :9

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: NP_741730.1
• Gene: ser-7 / 180565
• WormBaseID: WBGene00004780
• Length: 435
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 146/508 - (28%)
• Similarity: 215/508 - (42%)
• Gaps: 117/508 - (23%)

  Fly    73 ATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAF----------LFLFSFATVFGNS 127
            |.:..:||....|....|:...||      .|..|||.|.:|          :......|..||:
 Worm     2 ARAVNISPFASYTVVPITSAWPPD------DLKADRVQLASFTTGKALLAIAILAMIIMTTVGNA 60

  Fly   128 LVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLF 192
            ||.|||:..|.|....|:.:.||||||..|||||||. ||.::|.:.|..|:..|.::.:.|:..
 Worm    61 LVCLAVLLVRKLKHPQNFLLVSLAVADFFVGLVVMPL-ALIDLLFDKWPLGSTMCSVYTTSDLTL 124

  Fly   193 STASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMP 257
            .||||:|||.||:|||..|:.|..|..:.|.||....||.|||.::.:|..:.:......||
 Worm   125 CTASIVNLCAISVDRYLVISSPLRYSAKRTTKRIMMYIACVWIIAAIVSISSHIIANLLNDG--- 186

  Fly   258 AY-----KCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMASGEL 317
            .|     .|....|..|..:::.||||.|..:||....:|:|||            :.|.|...|
 Worm   187 TYVDDTGTCQVIPHFIYQSYATIISFYAPTFIMVILNIKIWRAA------------KRLAAQDRL 239

  Fly   318 QLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTS--TPEEPD 380
                                               :||.:|........:|...|..  ..:|..
 Worm   240 -----------------------------------MSHCNSVDASERPRNGSAETKDFLNEKETI 269

  Fly   381 DEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEK------------KAAKTLGIVMGVFIICWL 433
            |.|.....|:..:|...:.:.: |.|..|.|:..|            ||.||||::|.|||||||
 Worm   270 DVPKKERANSTNSRLFKLERKY-LHRPSAFFSAAKGPLIRQTEKSECKARKTLGVIMSVFIICWL 333

  Fly   434 PFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLL-CMCC---- 493
            |||::.:...|.:..   .:.:..:..|||:.||.:||:||..::::||..|..:| |.|.
 Worm   334 PFFILAIFKSFGMWI---PDWLDLLALWLGYSNSTLNPLIYCKYNKEFRIPFREMLACRCATLQT 395

  Fly   494 ---PRKIRRKYQPTMRSKSQCHVAAAMVAASTSFGYHSVNQIDRTLMXRQLSS 543
               .:....:|.|.:|.::|          |:|:         |.|:.|:..|
 Worm   396 VMRQQSFTSRYGPPVRYRTQ----------SSSY---------RPLLSRRNDS 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tm_4	123..>295	CDD:304433	68/176 (39%)
		7tm_1	125..474	CDD:278431	114/367 (31%)
ser-7	NP_741730.1	7tmA_5-HT7	42..382	CDD:320452	119/394 (30%)
		TM helix 1	44..68	CDD:320452	8/23 (35%)
		TM helix 2	77..99	CDD:320452	14/22 (64%)
		TM helix 3	115..137	CDD:320452	9/21 (43%)
		TM helix 4	160..176	CDD:320452	6/15 (40%)
		TM helix 5	201..224	CDD:320452	8/22 (36%)
		TM helix 6	315..340	CDD:320452	17/24 (71%)
		TM helix 7	350..375	CDD:320452	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910