Sequence 1: | NP_001263072.1 | Gene: | Dop1R2 / 43484 | FlyBaseID: | FBgn0266137 | Length: | 807 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_032334.2 | Gene: | Htr1a / 15550 | MGIID: | 96273 | Length: | 421 | Species: | Mus musculus |
Alignment Length: | 446 | Identity: | 158/446 - (35%) |
---|---|---|---|
Similarity: | 229/446 - (51%) | Gaps: | 56/446 - (12%) |
- Green bases have known domain annotations that are detailed below.
Fly 68 NATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVILA 132
Fly 133 VIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTASI 197
Fly 198 LNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARDGEMPAYKCT 262
Fly 263 FTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSL--KIGTKQVLMASG-------ELQ 318
Fly 319 LTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHG-------GGTTTSTP 376
Fly 377 ---EEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVV 438
Fly 439 NLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLL-CMCC 493 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Dop1R2 | NP_001263072.1 | 7tm_4 | 123..>295 | CDD:304433 | 79/171 (46%) |
7tm_1 | 125..474 | CDD:278431 | 135/367 (37%) | ||
Htr1a | NP_032334.2 | 7tm_4 | 48..>169 | CDD:304433 | 60/121 (50%) |
7tm_1 | 53..400 | CDD:278431 | 135/367 (37%) | ||
Agonist binding. /evidence=ECO:0000250 | 112..121 | 4/8 (50%) | |||
DRY motif, important for ligand-induced conformation changes. /evidence=ECO:0000250 | 133..135 | 1/1 (100%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 237..268 | 4/30 (13%) | |||
Agonist binding. /evidence=ECO:0000250 | 358..362 | 3/3 (100%) | |||
NPxxY motif, important for ligand-induced conformation changes and signaling. /evidence=ECO:0000250 | 396..400 | 3/3 (100%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |