Protein Alignment Dop1R2 and Oamb

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_061508856.1
• Gene: Oamb / 1272230
• VectorBaseID: AGAMI1_010906
• Length: 592
• Species: Anopheles gambiae
• Alignment Length: 614
• Identity: 192/614 - (31%)
• Similarity: 260/614 - (42%)
• Gaps: 206/614 - (33%)

  Fly   105 PNDRVGLLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYE 169
            |.:.|.|....|: :...:.||.|||.||:....|.:.||:||.||||||.||||.|:||||.:|
Mosquito    18 PTNLVSLAVLAFI-NVLVIVGNCLVIAAVLCSHKLRSVTNFFIVSLAVADLLVGLAVLPFSATWE 81

  Fly   170 VLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVW 234
            |.: .|.||..||.||.::||...||||||||.||||||.|:|.|.:||..|:.:||..|||.:|
Mosquito    82 VFK-VWIFGDVWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTRRAKSLIAGLW 145

  Fly   235 ICSSAISFPAIVWWRAARDGEMPAYK----------------------CTFTEHLGYLVFSSTIS 277
            :.|..|.||.:|.|:..:..|...|:                      |..|...||:|:|:..|
Mosquito   146 VLSFVICFPPLVGWKEQKVKENVYYQYGNYTLVSVTPSPAPPLPCPWTCELTNDAGYVVYSALGS 210

  Fly   278 FYLPLLVMVFTYCRIYRAAVIQTRSLKIG---TKQVLMASGELQLTLRIHRG------------- 326
            ||:|:.||:|.|.|||||||..||::..|   ||.:.....:.:||||||||
Mosquito   211 FYIPMFVMLFFYWRIYRAAVRTTRAINQGFRTTKGMGNRFDDNRLTLRIHRGRGSTSAPLHESPH 275

  Fly   327 --GTTRDQQNQVS-------------------GG------------------------------- 339
              |:|......:.                   ||
Mosquito   276 SNGSTHSTTTSIGSASPERLSRYSTRGKLVGHGGTVPHPTAHHEKIKISVSYPSTENVAQSCHAE 340

  Fly   340 GGGG-------------------GGGGGGGGSLSHSHSHSHHHHHNH------------------ 367
            .|||                   ||||.||..|.::..:|..:..:.
Mosquito   341 AGGGPSSPAVAAAGAMATSSSSTGGGGSGGTKLLYAVHYSSANGRDSNASQIFRRPSKEQQMGSV 405

  Fly   368 -GGGTTTSTPEEPDDEPLSALHNNGLARHRHMGKNF------------SLSRKLAKFAKEKKAAK 419
             ||.|...|..|...:......:     ||..|.:|            ::..::.:|..|.||||
Mosquito   406 LGGSTQYLTVSEQQQQQQQQQQS-----HRERGSSFLSPRASKRMGKRNIKAQVKRFRMETKAAK 465

  Fly   420 TLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRA 484
            ||.|::|:|::||||||.:.|:..||.:||  .|::.:||.|:|:.||.:||:|||.:|:|||.|
Mosquito   466 TLAIIVGLFVLCWLPFFTMYLVRPFCDDCI--NELLFSIVFWIGYCNSAINPMIYALFSKDFRFA 528

  Fly   485 FVRLLCMCCPRKIRRKYQPTMRSKSQCHVAAAMVAASTSFGYHSVNQIDRTLMXRQLSSCSTCSG 549
            |.|::|.|                                                     .|||
Mosquito   529 FKRIICRC-----------------------------------------------------FCSG 540

  Fly   550 GSNCG--GSR--SAHHQHHSSGTATPSSS 574
            |...|  |||  |...|..:.|..|||.|
Mosquito   541 GRFAGAVGSRRGSDMSQMRAHGGRTPSIS 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	168/502 (33%)
		TM helix 2	143..169	CDD:320195	19/25 (76%)
		TM helix 3	182..212	CDD:320195	20/29 (69%)
		TM helix 4	224..246	CDD:320195	10/21 (48%)
		TM helix 5	266..295	CDD:320195	15/28 (54%)
		TM helix 6	297..442	CDD:320195	56/262 (21%)
		TM helix 7	453..478	CDD:320195	12/24 (50%)
Oamb	XP_061508856.1	None