Protein Alignment Dop1R2 and LOC116411706

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_031760361.1
• Gene: LOC116411706 / 116411706
• XenbaseID: XB-GENE-29097575
• Length: 402
• Species: Xenopus tropicalis
• Alignment Length: 443
• Identity: 118/443 - (26%)
• Similarity: 196/443 - (44%)
• Gaps: 93/443 - (20%)

  Fly    68 NATT-SATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATVFGNSLVIL 131
            |.|. :.|:.:|...|      ||.:|:..:           :.|:..:......||.||:||||
 Frog    19 NVTNINQTNTSLVDVM------GTQSPQITM-----------IILVTVISCLILVTVLGNTLVIL 66

  Fly   132 AVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDVLFSTAS 196
            |.|.:|.|...:|:|:.:||:.|..:|...:||...| |....|..|...|.:|..:|.|..|||
 Frog    67 AFIEDRRLRNRSNFFLLNLAICDFFIGAFCIPFYVPY-VFTGKWLLGKFLCKLWLIVDNLMCTAS 130

  Fly   197 ILNLCVISLDRYWAITDPFSYPMRMTVKRAAGL----IAAVWICSSAISFPAIVWWRAARDGE-- 255
            ..|:.:||.||:.::|   ...:..::::..|.    :|.|||.:|.:..|||::|... ||:
 Frog   131 AFNVVLISYDRFLSVT---MAVLHRSIEKEHGRTVLNMALVWILASLLYSPAIIFWEYV-DGDKS 191

  Fly   256 ------MPAYKCTFTEHLGYLVFSSTISFYLPLLVMVF----TYCRIYRAAVIQTRSLKIGTKQV 310
                  :|.|...:.    :|:.:||..|.||||.:.|    .||.      |::||.|   ||.
 Frog   192 IPTDLCLPGYFYAWY----FLLGASTFDFLLPLLSISFFNLSLYCN------IRSRSRK---KQH 243

  Fly   311 LMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTST 375
            ::.| .:...|                            .|:.:..:..|.:..|| |.....:|
 Frog   244 IVTS-PIDSNL----------------------------DGNPARPYIISGNDFHN-GAVKDLNT 278

  Fly   376 PE-EPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVN 439
            |: :.....|....:|.|..||.. :....:..:.|.:::||.||:|.:::.||.:||.|:.::.
 Frog   279 PQYKKGKRSLCCFFSNVLPLHRDQ-QTVRYNVHVIKLSRDKKIAKSLSVLVCVFGMCWAPYSLLM 342

  Fly   440 LLSGFCIECIEHEEIVSA----IVTWLGWINSCMNPVIYACWSRDFRRAFVRL 488
            .:...|     |:..:.:    |..||.||||.:||.:|......||:||.::
 Frog   343 TIRAAC-----HDNCIDSYWYDITFWLLWINSSVNPFLYPLCHESFRKAFAKV 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	107/383 (28%)
		TM helix 2	143..169	CDD:320195	8/25 (32%)
		TM helix 3	182..212	CDD:320195	12/29 (41%)
		TM helix 4	224..246	CDD:320195	8/25 (32%)
		TM helix 5	266..295	CDD:320195	11/32 (34%)
		TM helix 6	297..442	CDD:320195	31/145 (21%)
		TM helix 7	453..478	CDD:320195	10/28 (36%)
LOC116411706	XP_031760361.1	7tmA_Histamine_H3R_H4R	44..387	CDD:320176	108/396 (27%)
		TM helix 1	45..71	CDD:320176	11/25 (44%)
		TM helix 2	78..105	CDD:320176	9/27 (33%)
		TM helix 3	116..146	CDD:320176	12/29 (41%)
		TM helix 4	161..179	CDD:320176	5/17 (29%)
		TM helix 5	204..234	CDD:320176	11/39 (28%)
		TM helix 6	315..345	CDD:320176	10/29 (34%)
		TM helix 7	355..380	CDD:320176	10/24 (42%)