Protein Alignment Dop1R2 and adra2b

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_002932610.1
• Gene: adra2b / 100485811
• XenbaseID: XB-GENE-999343
• Length: 410
• Species: Xenopus tropicalis
• Alignment Length: 427
• Identity: 132/427 - (30%)
• Similarity: 197/427 - (46%)
• Gaps: 89/427 - (20%)

  Fly   111 LLAFLFLFSFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTW 175
            ::.||.||   |:|||.|||:||:..|.|....|.|:.|||.||.||..:::|||...|:: ..|
 Frog    18 IITFLVLF---TIFGNVLVIIAVLTSRSLKAPQNLFLVSLAAADILVATLIIPFSLANELM-GYW 78

  Fly   176 FFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAI 240
            :||..||:::.:|||||.|:||::||.|||||||:::....|..:.|.||...:|..||..::.|
 Frog    79 YFGKTWCEMYLALDVLFCTSSIVHLCAISLDRYWSVSQAIEYNSKRTPKRIKCIILIVWTLAALI 143

  Fly   241 SFPAIVWWRAARDGEMPAYKCTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKI 305
            |.|.:::...::| :....:|...|...|::.||..||:.|.|:|:..|.|||..|..:.|....
 Frog   144 SLPPLIYKGKSKD-QNAKPECKLNEEPWYILSSSICSFFAPCLIMILVYLRIYLIAKRRNRKNST 207

  Fly   306 GTKQVLMASGELQLTLR---------------------------IHRG----GTTRDQQNQVSGG 339
            ..|...||.|....|.:                           :|.|    .:||:::|
 Frog   208 DKKLKKMAPGLFSRTNKHSLNSSHTQTQCGIISSQEKTGLALDDLHCGVPVLSSTREERN----- 267

  Fly   340 GGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPDDEPLSALHNNG------------- 391
                          .||.|..                .:|..|.|.  |.||
 Frog   268 --------------GHSESFG----------------LQPQGENLK--HTNGCEPAVMDTVATVK 300

  Fly   392 ---LARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFCIECIEHEE 453
               |........:.|.::|.:...:||:....|.:|:|||::||.|||....|...|.|.....:
 Frog   301 GVMLMPKGAKDSDLSSAKKKSYINREKRFTFVLAVVIGVFVLCWFPFFFTYSLGAICTELCYIPD 365

  Fly   454 IVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLC 490
            .|.....|:|:.||.:|||||..:::|||:||.|:||
 Frog   366 SVFQFFFWIGYCNSSLNPVIYTIFNQDFRKAFRRILC 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	123/409 (30%)
		TM helix 2	143..169	CDD:320195	12/25 (48%)
		TM helix 3	182..212	CDD:320195	18/29 (62%)
		TM helix 4	224..246	CDD:320195	8/21 (38%)
		TM helix 5	266..295	CDD:320195	12/28 (43%)
		TM helix 6	297..442	CDD:320195	35/191 (18%)
		TM helix 7	453..478	CDD:320195	10/24 (42%)
adra2b	XP_002932610.1	7tmA_alpha2B_AR	7..397	CDD:320444	127/420 (30%)
		TM helix 1	14..40	CDD:320444	13/24 (54%)
		TM helix 2	47..73	CDD:320444	12/25 (48%)
		TM helix 3	85..115	CDD:320444	18/29 (62%)
		TM helix 4	127..150	CDD:320444	8/22 (36%)
		TM helix 5	168..197	CDD:320444	12/28 (43%)
		TM helix 6	324..354	CDD:320444	12/29 (41%)
		TM helix 7	365..390	CDD:320444	10/24 (42%)