Protein Alignment Dop1R2 and LOC100331077

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_002667517.2
• Gene: LOC100331077 / 100331077
• -ID: -
• Length: 396
• Species: Danio rerio
• Alignment Length: 446
• Identity: 119/446 - (26%)
• Similarity: 192/446 - (43%)
• Gaps: 93/446 - (20%)

  Fly    75 SATLSPAMVATGG----GGTTTPEPDLSE-------------FLEALPNDRVGLLAFLFLFSFAT 122
            |.|..|:|   |.    ....|.||.:|.             .|..|....|.|:|.:
Zfish     5 SLTCRPSM---GNHHHCDANMTREPAVSNATAVRRDAGFAGPVLALLTGMMVVLIALI------- 59

  Fly   123 VFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRS 187
            |.||:|||:|...::.|...:|||:.:||::|.|||...:|....| :|...|..|...|.:|..
Zfish    60 VCGNALVIVAFKMDKSLRKQSNYFLLNLAISDFLVGAFCIPVYMPY-ILTGKWMLGKGLCKLWLV 123

  Fly   188 LDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGL-IAAVWICSSAISFPAIVWW-RA 250
            :|.|..|||:.|:.:||.|||.::|...||..:..:...|.| ||.|||.:..:..|:|::| :.
Zfish   124 VDYLLCTASVFNIVLISYDRYLSVTKAVSYRAKQGMTHFAVLKIAVVWILAFLLYGPSILFWEQL 188

  Fly   251 ARDGEMPAYKCTFTEHL---GYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLM 312
            .....:|..:| |.|..   .:|:.:|.|.|::|.|.:.|....||    |..|..::|.:.
Zfish   189 TGRSRVPDDEC-FAEFYYTWYFLLSASVIEFFVPFLSVAFFNISIY----INIRRRRLGNRS--- 245

  Fly   313 ASGELQLTLRIHRGGTT-RDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTP 376
                   ..:.|...|. ||:                     :|..:....:.......:||...
Zfish   246 -------ESKCHNSATLYRDR---------------------THMSTRMCWNSLALKNKSTTDGE 282

  Fly   377 EEPDDEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLL 441
            :.|:.:.||..               .:.|  ::..::||.||:|.|::.||.:||.|:.::.::
Zfish   283 KRPESDGLSMR---------------CVQR--SRLRQDKKIAKSLAIIVCVFAVCWAPYTLLMIV 330

  Fly   442 SGFCI-ECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRK 496
            ...|. :|:.....  .:..||.|:||.:||.:|......|||||.::|   |||:
Zfish   331 RAACRGDCVSQHWY--EVTFWLLWLNSAINPFLYPLCHSSFRRAFFKIL---CPRQ 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	99/369 (27%)
		TM helix 2	143..169	CDD:320195	10/25 (40%)
		TM helix 3	182..212	CDD:320195	13/29 (45%)
		TM helix 4	224..246	CDD:320195	8/22 (36%)
		TM helix 5	266..295	CDD:320195	9/31 (29%)
		TM helix 6	297..442	CDD:320195	25/145 (17%)
		TM helix 7	453..478	CDD:320195	8/24 (33%)
LOC100331077	XP_002667517.2	7tm_GPCRs	46..373	CDD:475119	103/389 (26%)
		TM helix 1	48..72	CDD:410628	11/30 (37%)
		TM helix 2	81..103	CDD:410628	10/21 (48%)
		TM helix 3	119..141	CDD:410628	8/21 (38%)
		TM helix 4	165..181	CDD:410628	6/15 (40%)
		TM helix 5	207..230	CDD:410628	7/22 (32%)
		TM helix 6	307..329	CDD:410628	9/21 (43%)
		TM helix 7	341..366	CDD:410628	8/26 (31%)