Protein Alignment Dop1R2 and adra1ba

DIOPT Version :10

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_001922013.4
• Gene: adra1ba / 100149100
• ZFINID: ZDB-GENE-120510-1
• Length: 486
• Species: Danio rerio
• Alignment Length: 536
• Identity: 180/536 - (33%)
• Similarity: 264/536 - (49%)
• Gaps: 97/536 - (18%)

  Fly    59 LPTSTELVLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLFLFSFATV 123
            :.:.|:...|..::|:|.....:..::.|.||......||   .|||   :|::...|:. ||.|
Zfish     1 MSSDTDHAANFLSNASSELSDVSNSSSSGNGTAPSSFSLS---RALP---LGMVLGAFIV-FAIV 58

  Fly   124 FGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSL 188
             ||.||||:|:..|:|...|||||.:||:||.|:...|:|.||..|:| |.|.||..:||||.::
Zfish    59 -GNILVILSVVCNRHLRIPTNYFIINLAMADLLLSTTVLPVSATREIL-NYWVFGRIFCDIWAAV 121

  Fly   189 DVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAIVWWRAARD 253
            |||..||||::|||||:|||..:..|..||..:|.|||...:..||:.:..||...::.|:
Zfish   122 DVLCCTASIMSLCVISIDRYIGVRYPLQYPSIVTEKRALLAMLGVWVLAFVISIGPLLGWK---- 182

  Fly   254 GEMPAYK---CTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMASG 315
             |.|:..   |..||...|.:|||..|||:||.|::..|||:|..|...|::|:.|..:..|.|.
Zfish   183 -EPPSEDDTVCLITEEPFYALFSSLGSFYIPLAVILAMYCRVYIVAKRTTKNLEAGVMKEHMDSN 246

  Fly   316 ELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEPD 380
            |  ||||||..| ::.|::...|                  |..|
Zfish   247 E--LTLRIHYKG-SQTQEDCTKG------------------HLRS-------------------- 270

  Fly   381 DEPLSALHNNGLARHRHMGKNFSLSRKLAKFAKEKKAAKTLGIVMGVFIICWLPFFVVNLLSGFC 445
                                  ||:.||.||::|||||||||:|:|:||:||||||:...:..|.
Zfish   271 ----------------------SLTVKLLKFSREKKAAKTLGVVVGMFILCWLPFFLALPIGSFN 313

  Fly   446 IECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLL-CMCCPRKIR--RKYQPTMRS 507
            .. :...|....::.|||:.|||:||:||.|:||:|::||:|:| |.|..:|.:  |.|...:.:
Zfish   314 TS-LRPPETFFKVIFWLGYFNSCLNPIIYPCYSREFKQAFIRILRCQCQQKKQQGWRAYNYRVPN 377

  Fly   508 KSQCHVAAAMVAASTSFGYHSVNQIDRTLMXRQLSS------------CSTCSGGSNCGGSRSAH 560
            .:..:...:.:..:.|....:.:|...||..|.:.|            | |.|..|:..||....
Zfish   378 ANHVYSDTSSICMNGSLQTLAPSQPSPTLFSRVVGSRPASGLLPGWGPC-TSSSSSSLSGSPFPG 441

  Fly   561 HQHHSSGTATPSSSQR 576
            .....|...:|..|.|
Zfish   442 MMRSGSQATSPCKSNR 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tmA_Dop1R2-like	122..485	CDD:320195	139/365 (38%)
		TM helix 2	143..169	CDD:320195	14/25 (56%)
		TM helix 3	182..212	CDD:320195	19/29 (66%)
		TM helix 4	224..246	CDD:320195	7/21 (33%)
		TM helix 5	266..295	CDD:320195	14/28 (50%)
		TM helix 6	297..442	CDD:320195	42/144 (29%)
		TM helix 7	453..478	CDD:320195	12/24 (50%)
adra1ba	XP_001922013.4	None