Protein Alignment Dop1R2 and adrb2b

DIOPT Version :9

• Sequence 1: NP_001263072.1
• Gene: Dop1R2 / 43484
• FlyBaseID: FBgn0266137
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: NP_001082940.2
• Gene: adrb2b / 100037315
• ZFINID: ZDB-GENE-070410-32
• Length: 409
• Species: Danio rerio
• Alignment Length: 522
• Identity: 160/522 - (30%)
• Similarity: 236/522 - (45%)
• Gaps: 138/522 - (26%)

  Fly    62 STELVLNATTSATSATLSPAMVATGGGGTTTPEPDLSEFLEALPNDRVGLLAFLF-LFSFATVFG 125
            :|.|.:|.:....::  ||..::            :||:.:|    .|.|::.|. :.....|||
Zfish    11 NTSLYMNISAGLNAS--SPVSLS------------VSEYSDA----EVVLISILIGILVLVIVFG 57

  Fly   126 NSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYEVLENTWFFGTDWCDIWRSLDV 190
            |:|||.|::|.:.|.|.|||||:|||.||.::||:|:||.|.| :|.|||.||..:|:.|.:.||
Zfish    58 NALVISAIVRFQRLQTVTNYFISSLACADLVMGLMVVPFGACY-ILLNTWHFGNFFCEFWTATDV 121

  Fly   191 LFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVWICSSAISFPAI--VWWRAARD 253
            |..||||..||||:||||.||..|..|...:|.::|.|::..||..::.|||..|  .||.:...
Zfish   122 LCVTASIETLCVIALDRYIAIMWPLRYQSMLTKRKACGMVIGVWAVAALISFLPIHMEWWVSDEP 186

  Fly   254 GEMPAYK----CTFTEHLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVIQTRSLKIGTKQVLMAS 314
            ..:...:    |.|..:..|.|.||.||||:||::|.|.|.|:::.                 |.
Zfish   187 EALSCLEEPTCCDFNTNAAYAVTSSIISFYIPLVIMAFVYSRVFQE-----------------AR 234

  Fly   315 GELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHHHHNHGGGTTTSTPEEP 379
            .:||...||.  |..|.|.
Zfish   235 RQLQKIDRIE--GRIRTQS---------------------------------------------- 251

  Fly   380 DDEPLSALHNNGLARHRHMGKNFSLSRKLAKFA-KEKKAAKTLGIVMGVFIICWLPFFVVNLLSG 443
                ||....|.:...|            .||. |:.||.|||||:||.|.:|||||||:|:::
Zfish   252 ----LSTQEGNEIKNRR------------TKFCMKDHKALKTLGIIMGTFTLCWLPFFVLNVVA- 299

  Fly   444 FCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFVRLLCMCCPRKIRRKYQPTMRSK 508
             .|..:::..:...|:.|:|:.||..||:|| |.|.:||.||..:||.      |..:.|:.|||
Zfish   300 -AIWKMDNIMLPFRILNWIGYANSAFNPLIY-CRSPEFRCAFQEILCW------RPSHLPSTRSK 356

  Fly   509 SQCHVAAAMVAASTSFGY----HSVNQIDRTLMXRQLSSCSTCSGGSNC--GGSRSAHHQHHSSG 567
            .               ||    ||.....:|...|:.|.......|:.|  .|:::.:..::.:.
Zfish   357 K---------------GYLYSGHSWKVHTKTTRPREPSPACETEIGAECLTAGTKNKNGNYNKTV 406

  Fly   568 TA 569
            |:
Zfish   407 TS 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop1R2	NP_001263072.1	7tm_4	123..>295	CDD:304433	82/177 (46%)
		7tm_1	125..474	CDD:278431	121/355 (34%)
adrb2b	NP_001082940.2	7tm_GPCRs	41..339	CDD:333717	131/382 (34%)
		TM helix 1	43..67	CDD:320095	9/23 (39%)
		TM helix 2	76..98	CDD:320095	14/21 (67%)
		TM helix 3	114..136	CDD:320095	12/21 (57%)
		TM helix 4	159..175	CDD:320095	6/15 (40%)
		TM helix 5	204..227	CDD:320095	12/22 (55%)
		TM helix 6	272..297	CDD:320095	17/24 (71%)
		TM helix 7	308..333	CDD:320095	10/25 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910