DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dop1R2 and htr1fa

DIOPT Version :9

Sequence 1:NP_001263072.1 Gene:Dop1R2 / 43484 FlyBaseID:FBgn0266137 Length:807 Species:Drosophila melanogaster
Sequence 2:XP_017213382.1 Gene:htr1fa / 100005344 ZFINID:ZDB-GENE-081105-125 Length:363 Species:Danio rerio


Alignment Length:393 Identity:128/393 - (32%)
Similarity:197/393 - (50%) Gaps:63/393 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   106 NDRVGLLAFLFLF-SFATVFGNSLVILAVIRERYLHTATNYFITSLAVADCLVGLVVMPFSALYE 169
            |..|.||:....| :..|...|.|||.|:|..|.||..:||.|.||||.|.||.::|||||.:| 
Zfish    19 NGDVVLLSLTLSFLAILTTAMNCLVITAIIVTRKLHHPSNYLICSLAVTDLLVAILVMPFSIIY- 82

  Fly   170 VLENTWFFGTDWCDIWRSLDVLFSTASILNLCVISLDRYWAITDPFSYPMRMTVKRAAGLIAAVW 234
            :.::||..|...|..|.|:|:...|.|||:|..|::|||.||||...|..:.|..|||.:|:.||
Zfish    83 IAKDTWLIGEALCKFWLSVDITCCTCSILHLAAIAVDRYRAITDAVEYSRKRTSLRAAIMISVVW 147

  Fly   235 ICSSAISFPAIVWWRAARDGEMPAYKCTFTE-HLGYLVFSSTISFYLPLLVMVFTYCRIYRAAVI 298
            :.:..||.|.|:    .|:||  ..:|.... ::..:::|:..:||:||::::..|.:|||||  
Zfish   148 LLAIVISLPPIL----LRNGE--ENECIIVHTNIASMLYSTFGAFYIPLILILILYYKIYRAA-- 204

  Fly   299 QTRSLKIGTKQVLMASGELQLTLRIHRGGTTRDQQNQVSGGGGGGGGGGGGGGSLSHSHSHSHHH 363
                                .|| .||..|:...:::::|                        |
Zfish   205 --------------------KTL-YHRRRTSCLNKSEMNG------------------------H 224

  Fly   364 HHNHGGGTTTSTPE--EPDDEPLSALHNNG-----LARHRHMGKNFSLSRKLAKFAKEKKAAKTL 421
            ..........:||:  .|.::.:|.....|     .||.....:..||.|......:|||||.||
Zfish   225 MLPKCSDREPTTPDTLSPPEKSMSEPSTEGDRVRITARSPKSRRERSLRRHRISNIREKKAATTL 289

  Fly   422 GIVMGVFIICWLPFFVVNLLSGFCIECIEHEEIVSAIVTWLGWINSCMNPVIYACWSRDFRRAFV 486
            |:::|.|::||||||:..::...|.........|:..:||||::||.:||:||..::.||:|||.
Zfish   290 GLIIGAFVVCWLPFFIHEVIYNICTVSCSRSVAVTNFLTWLGYLNSLINPLIYTIFNEDFKRAFQ 354

  Fly   487 RLL 489
            :::
Zfish   355 KII 357

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dop1R2NP_001263072.1 7tm_4 123..>295 CDD:304433 69/172 (40%)
7tm_1 125..474 CDD:278431 115/356 (32%)
htr1faXP_017213382.1 7tm_GPCRs 23..354 CDD:333717 125/384 (33%)
TM helix 1 25..49 CDD:320095 8/23 (35%)
TM helix 2 58..80 CDD:320095 14/21 (67%)
TM helix 3 96..118 CDD:320095 9/21 (43%)
TM helix 4 141..157 CDD:320095 5/15 (33%)
TM helix 5 175..198 CDD:320095 5/22 (23%)
TM helix 6 283..308 CDD:320095 15/24 (63%)
TM helix 7 321..346 CDD:320095 11/24 (46%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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