DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1907 and aralar1

DIOPT Version :9

Sequence 1:	NP_651703.1	Gene:	CG1907 / 43483	FlyBaseID:	FBgn0039674	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001247368.1	Gene:	aralar1 / 43616	FlyBaseID:	FBgn0028646	Length:	707	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	87/303 - (28%)
Similarity:	137/303 - (45%)	Gaps:	38/303 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VATNAIKFLFGGLSG-MGATMVVQPLDLVKTRMQISGAGS--GKKEYRSSLHCIQTIVSKEGPLA 75
            |..::.:|..|..:| :||| ||.|:||||||||...|||  |:..||:|..|.:.:|..||.:.
  Fly   351 VLESSYRFTLGSFAGAVGAT-VVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMG 414

  Fly    76 LYQGIGAALLRQATYTTGRLGMYTYLNDLFREKFQRSPGITDSMA---MGTIAGACGAFIGTPAE 137
            ||:|    ||.|.........:...:|||.|:|.....|...:.|   .|..|||.......|.|
  Fly   415 LYRG----LLPQLMGVAPEKAIKLTVNDLVRDKLTDKKGNIPTWAEVLAGGCAGASQVVFTNPLE 475

  Fly   138 VALVRMTSDGRLPVAER-RNYTNVANALARITREEGLTALWRGSLPTVGRAMVVNMTQLASYSQF 201
            :..:|:...|.:....: |.::        :.||.||..|::|:...:.|.:..:.....:|:..
  Fly   476 IVKIRLQVAGEIASGSKIRAWS--------VVRELGLFGLYKGARACLLRDVPFSAIYFPTYAHT 532

  Fly   202 KTY------FRHGPLQMEEGIKLHFCASMLSGLLTTITSMPLDIAKTRIQNMKMVDGKPEYRGTA 260
            |..      :.| ||.:       ..|..::|:.......|.|:.|||:|.:.. .|:..|.|..
  Fly   533 KAMMADKDGYNH-PLTL-------LAAGAIAGVPAASLVTPADVIKTRLQVVAR-SGQTTYTGVW 588

  Fly   261 DVLLRVARQEGVFALWKGFTPYYCRLGPH---TVLTFIILEQL 300
            |...::..:||..|.|||......|..|.   |::|:.:|::|
  Fly   589 DATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELLQRL 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1907	NP_651703.1	Mito_carr	16..109	CDD:278578	38/95 (40%)
		Mito_carr	118..207	CDD:278578	19/98 (19%)
		Mito_carr	219..307	CDD:278578	24/85 (28%)
aralar1	NP_001247368.1	EF-hand_7	35..99	CDD:290234
		EF-hand_8	51..99	CDD:290545
		EF-hand_7	81..134	CDD:290234
		EFh	84..135	CDD:298682
		EF-hand_7	111..173	CDD:290234
		Mito_carr	350..448	CDD:278578	40/101 (40%)
		PTZ00169	358..631	CDD:240302	85/294 (29%)
		Mito_carr	449..539	CDD:278578	20/97 (21%)
		Mito_carr	544..633	CDD:278578	27/97 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441998
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840