DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1907 and slc25a11

DIOPT Version :9

Sequence 1:	NP_651703.1	Gene:	CG1907 / 43483	FlyBaseID:	FBgn0039674	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001002099.1	Gene:	slc25a11 / 415189	ZFINID:	ZDB-GENE-040625-79	Length:	308	Species:	Danio rerio

Alignment Length:	317	Identity:	187/317 - (58%)
Similarity:	225/317 - (70%)	Gaps:	15/317 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSATSVQEAPKKAVATNAIKFLFGGLSGMGATMVVQPLDLVKTRMQISGAGSGKKEYRSSLHCIQ 65
            |:|.:....||  .:..:||||||||:|||||:.||||||||.|||:||.||..:||::|.|.:.
Zfish     1 MAAAADTAKPK--TSPKSIKFLFGGLAGMGATVFVQPLDLVKNRMQLSGQGSKAREYKTSFHAVG 63

  Fly    66 TIVSKEGPLALYQGIGAALLRQATYTTGRLGMYTYLNDLFREKFQRSPGITDSMAMGTIAGACGA 130
            :|:..||...:|.|:.|.|||||||||.|||:||.|.:...:.....|.......:|..|||.||
Zfish    64 SILRNEGVRGIYTGLSAGLLRQATYTTTRLGIYTILFERMSKADGTPPNFFMKALIGMTAGATGA 128

  Fly   131 FIGTPAEVALVRMTSDGRLPVAERRNYTNVANALARITREEGLTALWRGSLPTVGRAMVVNMTQL 195
            |:||||||||:|||:|||||..:||.||||.|||.|||||||:|.||||.:||:.||:|||..||
Zfish   129 FVGTPAEVALIRMTADGRLPPDQRRGYTNVFNALVRITREEGVTTLWRGCIPTMARAVVVNAAQL 193

  Fly   196 ASYSQFKT------YFRHGPLQMEEGIKLHFCASMLSGLLTTITSMPLDIAKTRIQNMKMVDGKP 254
            |||||.|.      |||       :.|..||||||:|||:||..|||:||.|||||||:|:||||
Zfish   194 ASYSQSKQALLDSGYFR-------DDILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKP 251

  Fly   255 EYRGTADVLLRVARQEGVFALWKGFTPYYCRLGPHTVLTFIILEQLNQGYNKYVLGS 311
            ||....|||::|.|.||.|:|||||||||.|||||||||||.|||:|:.|..|.|.|
Zfish   252 EYNNGLDVLVKVIRNEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKFYKIYFLDS 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1907	NP_651703.1	Mito_carr	16..109	CDD:278578	53/92 (58%)
		Mito_carr	118..207	CDD:278578	61/94 (65%)
		Mito_carr	219..307	CDD:278578	63/87 (72%)
slc25a11	NP_001002099.1	Mito_carr	18..96	CDD:278578	49/77 (64%)
		PTZ00169	19..300	CDD:240302	177/287 (62%)
		Mito_carr	110..207	CDD:278578	60/96 (63%)
		Mito_carr	213..305	CDD:278578	64/91 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590896
Domainoid	1	1.000	141	1.000	Domainoid score	I4688
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2637
Inparanoid	1	1.050	359	1.000	Inparanoid score	I2171
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D404074at33208
OrthoFinder	1	1.000	-	-		FOG0004406
OrthoInspector	1	1.000	-	-		oto38825
orthoMCL	1	0.900	-	-		OOG6_101430
Panther	1	1.100	-	-	LDO	PTHR45618
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	1	1.000	-	-		X2168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800