DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1907 and misc-1

DIOPT Version :9

Sequence 1:	NP_651703.1	Gene:	CG1907 / 43483	FlyBaseID:	FBgn0039674	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_493694.2	Gene:	misc-1 / 173414	WormBaseID:	WBGene00015186	Length:	306	Species:	Caenorhabditis elegans

Alignment Length:	302	Identity:	185/302 - (61%)
Similarity:	224/302 - (74%)	Gaps:	5/302 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 NAIKFLFGGLSGMGATMVVQPLDLVKTRMQISGAGSGKKEYRSSLHCIQTIVSKEGPLALYQGIG 81
            |.:||.|||.:|||||:|||||||||.|||:||. :||||||||:|.:.:|:..||..|:|.|:.
Worm     9 NVVKFAFGGTAGMGATLVVQPLDLVKNRMQLSGT-TGKKEYRSSMHALTSIMKNEGVFAVYNGLS 72

  Fly    82 AALLRQATYTTGRLGMYTYLNDLFREKFQRSPGITDSMAMGTIAGACGAFIGTPAEVALVRMTSD 146
            |.|||||||||.|||.|.:|.:.|.|| .:.........:|..||..|:|:|||||:||:|||.|
Worm    73 AGLLRQATYTTTRLGTYAFLLERFTEK-DKPLSFGMKAVLGMTAGGIGSFVGTPAEIALIRMTGD 136

  Fly   147 GRLPVAERRNYTNVANALARITREEGLTALWRGSLPTVGRAMVVNMTQLASYSQFK-TYFRHGPL 210
            |||||.:|||||.|.|||.|||:|||:..||||..|||.||||||..|||:|||.| .....|.:
Worm   137 GRLPVEQRRNYTGVVNALTRITKEEGVLTLWRGCTPTVLRAMVVNAAQLATYSQAKQALLASGKV 201

  Fly   211 QMEEGIKLHFCASMLSGLLTTITSMPLDIAKTRIQNMKMVDGKPEYRGTADVLLRVARQEGVFAL 275
            |  :||..||.|||:|||.|||.|||:||||||||:||::||||||:...||..:|.:.||:|||
Worm   202 Q--DGIFCHFLASMISGLATTIASMPVDIAKTRIQSMKVIDGKPEYKNAFDVWGKVIKNEGIFAL 264

  Fly   276 WKGFTPYYCRLGPHTVLTFIILEQLNQGYNKYVLGSNKSTGL 317
            ||||||||.|||||||||||||||:|..|.:|||..:.::.|
Worm   265 WKGFTPYYMRLGPHTVLTFIILEQMNAAYFQYVLKRDVTSAL 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1907	NP_651703.1	Mito_carr	16..109	CDD:278578	57/91 (63%)
		Mito_carr	118..207	CDD:278578	56/89 (63%)
		Mito_carr	219..307	CDD:278578	63/87 (72%)
misc-1	NP_493694.2	Mito_carr	7..99	CDD:278578	56/90 (62%)
		Mito_carr	101..196	CDD:278578	56/94 (60%)
		Mito_carr	202..296	CDD:278578	66/95 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164162
Domainoid	1	1.000	137	1.000	Domainoid score	I3044
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2637
Inparanoid	1	1.050	359	1.000	Inparanoid score	I1294
Isobase	1	0.950	-	0	Normalized mean entropy	S777
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D404074at33208
OrthoFinder	1	1.000	-	-		FOG0004406
OrthoInspector	1	1.000	-	-		oto20062
orthoMCL	1	0.900	-	-		OOG6_101430
Panther	1	1.100	-	-	LDO	PTHR45618
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	1	1.000	-	-		X2168
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790