DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7568 and WDR5b

DIOPT Version :9

Sequence 1:	NP_001263071.1	Gene:	CG7568 / 43482	FlyBaseID:	FBgn0039673	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_192182.1	Gene:	WDR5b / 828189	AraportID:	AT4G02730	Length:	333	Species:	Arabidopsis thaliana

Alignment Length:	247	Identity:	68/247 - (27%)
Similarity:	118/247 - (47%)	Gaps:	14/247 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 DGKSIATASLDGSARIYDVETSHELQQLTHHGAEVIAARFNRDGQMLLTGSFDHSAAIWDVRSKS 300
            :..|...|...|:..||  :....|:.|..|.|.:...:|:.||.:|.:.|.|.:..:|...:.|
plant    14 NANSTGNAGTSGNVPIY--KPYRHLKTLEGHTAAISCVKFSNDGNLLASASVDKTMILWSATNYS 76

  Fly   301 LGHQLRGHSAELSNCVWNFSGSLIATGSLDNTARIWDTRKLDQELYLAARHSDEVLDVSFDAAGQ 365
            |.|:..|||:.:|:..|:.......:.|.|.|.||||.|...:.|.:...|::.|..|:|:....
plant    77 LIHRYEGHSSGISDLAWSSDSHYTCSASDDCTLRIWDARSPYECLKVLRGHTNFVFCVNFNPPSN 141

  Fly   366 LLATCSSDCTARVWRLEGSSELEMLSLMAGHSDEVSKVCFSPSGCMLLTASADNTARLWLTESGQ 430
            |:.:.|.|.|.|:|.::....:.|:.   .||..:|.|.|:..|.::::||.|.:.::|..:.|.
plant   142 LIVSGSFDETIRIWEVKTGKCVRMIK---AHSMPISSVHFNRDGSLIVSASHDGSCKIWDAKEGT 203

  Fly   431 CSQVLAGHEGEVFSCA-YSYAGDAILTASKDNSC--------RFWRXYDWYT 473
            |.:.|...:....|.| :|..|..||.|:.|::.        :|.:.|..:|
plant   204 CLKTLIDDKSPAVSFAKFSPNGKFILVATLDSTLKLSNYATGKFLKVYTGHT 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	65/238 (27%)
		WD40 repeat	122..158	CDD:293791
		WD40	154..467	CDD:238121	66/239 (28%)
		WD40 repeat	189..222	CDD:293791
		WD40 repeat	228..265	CDD:293791	7/28 (25%)
		WD40 repeat	270..306	CDD:293791	10/35 (29%)
		WD40 repeat	314..348	CDD:293791	10/33 (30%)
		WD40 repeat	355..393	CDD:293791	10/37 (27%)
		WD40 repeat	400..436	CDD:293791	10/35 (29%)
		WD40 repeat	442..466	CDD:293791	8/32 (25%)
WDR5b	NP_192182.1	WD40	26..>330	CDD:225201	65/235 (28%)
		WD40	35..330	CDD:238121	63/224 (28%)
		WD40 repeat	46..83	CDD:293791	10/36 (28%)
		WD40 repeat	89..126	CDD:293791	11/36 (31%)
		WD40 repeat	131..167	CDD:293791	10/35 (29%)
		WD40 repeat	174..209	CDD:293791	10/34 (29%)
		WD40 repeat	216..252	CDD:293791	9/35 (26%)
		WD40 repeat	260..297	CDD:293791
		WD40 repeat	303..329	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53955
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010