DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7568 and Wdr38

DIOPT Version :9

Sequence 1:	NP_001263071.1	Gene:	CG7568 / 43482	FlyBaseID:	FBgn0039673	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_083963.1	Gene:	Wdr38 / 76646	MGIID:	1923896	Length:	303	Species:	Mus musculus

Alignment Length:	264	Identity:	79/264 - (29%)
Similarity:	131/264 - (49%)	Gaps:	7/264 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 IVTGSFDGTAKVWSATSGQSLCTFYGHTAELVAAEFHPVDGKSIATASLDGSARIYDVETSHELQ 261
            ::|.|.||...||...||:.|....||...:.:..|.| ||:.||::|.|.|.|::||..|..|.
Mouse    41 LLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSP-DGRLIASSSSDHSIRLWDVARSKCLH 104

  Fly   262 QLTHHGAEVIAARFNRDGQMLLTGSFDHSAAIWDVRSKSLGHQLRGHSAELSNCVWNFSGSLIAT 326
            .|..|...|....|:.|.:.|.:|.:|..|.:|:|:|....|.|.||...:.:..::.:...:||
Mouse   105 VLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLAT 169

  Fly   327 GSLDNTARIWDTRKLDQ--ELYLAARHSDEVLDVSFDAAGQLLATCSSDCTARVWRLEGSSELEM 389
            ||.|:|..|||.|....  ..:....|:..:..:.:.|:| |||:.|.|.|..||: ..::.|.:
Mouse   170 GSWDSTVHIWDLRASTPVVSYHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWK-PTTNNLPL 232

  Fly   390 LSLMAGHSDEVSKVCFSPSGCMLLTASADNTARLWLTESGQCSQVLAGHEGEVFSCAYSYAGDAI 454
              .:.||:..|:.:.|||....|.:|....|.::|...:|:|.:.|.|......:|.::..|..:
Mouse   233 --QLKGHTIWVNSLAFSPDELKLASAGYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLL 295

  Fly   455 LTAS 458
            ::.:
Mouse   296 VSGA 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	79/264 (30%)
		WD40 repeat	122..158	CDD:293791
		WD40	154..467	CDD:238121	79/264 (30%)
		WD40 repeat	189..222	CDD:293791	9/24 (38%)
		WD40 repeat	228..265	CDD:293791	15/36 (42%)
		WD40 repeat	270..306	CDD:293791	11/35 (31%)
		WD40 repeat	314..348	CDD:293791	10/35 (29%)
		WD40 repeat	355..393	CDD:293791	11/37 (30%)
		WD40 repeat	400..436	CDD:293791	10/35 (29%)
		WD40 repeat	442..466	CDD:293791	2/17 (12%)
Wdr38	NP_083963.1	WD40	<18..300	CDD:225201	79/264 (30%)
		WD 1	24..63		9/21 (43%)
		WD40	25..300	CDD:238121	79/264 (30%)
		WD40 repeat	31..66	CDD:293791	9/24 (38%)
		WD 2	66..105		16/39 (41%)
		WD40 repeat	72..108	CDD:293791	15/36 (42%)
		WD 3	108..147		11/38 (29%)
		WD40 repeat	113..149	CDD:293791	11/35 (31%)
		WD 4	150..189		12/38 (32%)
		WD40 repeat	156..194	CDD:293791	10/37 (27%)
		WD 5	195..233		12/41 (29%)
		WD40 repeat	200..235	CDD:293791	11/38 (29%)
		WD 6	236..277		12/40 (30%)
		WD 7	279..303		2/21 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D872177at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010