DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7568 and wdr38

DIOPT Version :9

Sequence 1:	NP_001263071.1	Gene:	CG7568 / 43482	FlyBaseID:	FBgn0039673	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001017672.1	Gene:	wdr38 / 550366	ZFINID:	ZDB-GENE-050417-160	Length:	216	Species:	Danio rerio

Alignment Length:	168	Identity:	53/168 - (31%)
Similarity:	85/168 - (50%)	Gaps:	7/168 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 GTAKVWSATSGQSLCTFYGHTAELVAAEFHPVDGKSIATASLDGSARIY---DVETSHELQQLTH 265
            |...:|..::.:.|.:..|||..:....|.. ||:..|:||.|.|.|.:   .::.:|   .||.
Zfish    44 GKLYLWKTSTAKLLASVSGHTGPVKCCVFSS-DGRLFASASHDCSVRTWCNSSLKCTH---TLTA 104

  Fly   266 HGAEVIAARFNRDGQMLLTGSFDHSAAIWDVRSKSLGHQLRGHSAELSNCVWNFSGSLIATGSLD 330
            |...|....|:.|||.||:|.:|:.|.||.::|.:|..:|:||:|.:.:.|::.....:||||.|
Zfish   105 HRRSVETVSFSPDGQWLLSGGWDNRALIWSIQSGALLEELKGHNAAVQSSVFSSDSQSVATGSWD 169

  Fly   331 NTARIWDTRKLDQELYLAARHSDEVLDVSFDAAGQLLA 368
            ...|:|..|....|..:...|...|..:.|..||.|::
Zfish   170 RAVRVWKLRDRQAEAVVLQGHLGNVACLCFSVAGMLVS 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	53/168 (32%)
		WD40 repeat	122..158	CDD:293791
		WD40	154..467	CDD:238121	53/168 (32%)
		WD40 repeat	189..222	CDD:293791	3/17 (18%)
		WD40 repeat	228..265	CDD:293791	11/39 (28%)
		WD40 repeat	270..306	CDD:293791	14/35 (40%)
		WD40 repeat	314..348	CDD:293791	10/33 (30%)
		WD40 repeat	355..393	CDD:293791	5/14 (36%)
		WD40 repeat	400..436	CDD:293791
		WD40 repeat	442..466	CDD:293791
wdr38	NP_001017672.1	WD40	<14..>208	CDD:225201	53/168 (32%)
		WD40	<15..200	CDD:238121	49/159 (31%)
		WD40 repeat	26..62	CDD:293791	3/17 (18%)
		WD40 repeat	67..103	CDD:293791	10/39 (26%)
		WD40 repeat	110..145	CDD:293791	13/34 (38%)
		WD40 repeat	152..188	CDD:293791	10/35 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D872177at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940