DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7568 and WDR38

DIOPT Version :9

Sequence 1:NP_001263071.1 Gene:CG7568 / 43482 FlyBaseID:FBgn0039673 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_001263303.1 Gene:WDR38 / 401551 HGNCID:23745 Length:315 Species:Homo sapiens


Alignment Length:293 Identity:90/293 - (30%)
Similarity:140/293 - (47%) Gaps:16/293 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 QSGGSGNNLTTFSIIFS---DKIVTGSFDGTAKVWSATSGQSLCTFYGHTAELVAAEFHPVDGKS 239
            |.||..|     |..||   ..::|||.||....|...|||.|....|||..:....|.| ||..
Human    19 QHGGEVN-----SSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSP-DGHL 77

  Fly   240 IATASLDGSARIYDVETSHELQQLTHHGAEVIAARFNRDGQMLLTGSFDHSAAIWDVRSKSLGHQ 304
            .|:||.|.:.|::||..:..|:.|..|...|....|:.|.:.|.:|.:|....:|||:|..:...
Human    78 FASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRL 142

  Fly   305 LRGHSAELSNCVWNFSGSLIATGSLDNTARIWDTRKLDQELYLAA--RHSDEVLDVSFDAAGQLL 367
            |.||...:.:..::.:.:.:||||.|:|..|||.|.:...:...|  .||..:..:.:.|:| ||
Human   143 LVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASG-LL 206

  Fly   368 ATCSSDCTARVWRLEGSSELEMLSLMAGHSDEVSKVCFSPSGCMLLTASADNTARLWLTESGQCS 432
            |:.|.|.|..:|:...||   :|..:.||...|..:.|||....|.:|......::|...:|:|.
Human   207 ASGSWDKTIHIWKPTTSS---LLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCL 268

  Fly   433 QVL-AGHEGEVFSCAYSYAGDAILTASKDNSCR 464
            :.| .|......:||::..|..:::.:.|.:.|
Human   269 ETLKQGVLDVAHTCAFTPDGKILVSGAADQTRR 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7568NP_001263071.1 WD40 93..466 CDD:225201 90/293 (31%)
WD40 repeat 122..158 CDD:293791
WD40 154..467 CDD:238121 90/293 (31%)
WD40 repeat 189..222 CDD:293791 13/35 (37%)
WD40 repeat 228..265 CDD:293791 13/36 (36%)
WD40 repeat 270..306 CDD:293791 10/35 (29%)
WD40 repeat 314..348 CDD:293791 10/33 (30%)
WD40 repeat 355..393 CDD:293791 12/37 (32%)
WD40 repeat 400..436 CDD:293791 10/36 (28%)
WD40 repeat 442..466 CDD:293791 5/23 (22%)
WDR38NP_001263303.1 WD40 <11..299 CDD:225201 89/289 (31%)
WD 1 19..58 17/43 (40%)
WD40 20..301 CDD:238121 88/290 (30%)
WD40 repeat 26..61 CDD:293791 13/34 (38%)
WD 2 61..100 15/39 (38%)
WD40 repeat 67..103 CDD:293791 13/36 (36%)
WD 3 103..142 11/38 (29%)
WD40 repeat 108..144 CDD:293791 10/35 (29%)
WD 4 145..184 12/38 (32%)
WD40 repeat 151..189 CDD:293791 11/37 (30%)
WD 5 190..228 14/41 (34%)
WD40 repeat 195..230 CDD:293791 12/38 (32%)
WD 6 231..272 11/40 (28%)
WD40 repeat 236..272 CDD:293791 9/35 (26%)
WD 7 275..313 5/27 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 295..315 2/7 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D872177at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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