DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7568 and CG10459

DIOPT Version :9

Sequence 1:	NP_001263071.1	Gene:	CG7568 / 43482	FlyBaseID:	FBgn0039673	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_610513.2	Gene:	CG10459 / 36000	FlyBaseID:	FBgn0033440	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	332	Identity:	66/332 - (19%)
Similarity:	119/332 - (35%)	Gaps:	74/332 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 GHDNVVFSVGFNFPHWLVYLQSGGSGNNLTTFSIIFSDKIVTGSFDGTAKVWSATSGQSLCTFYG 222
            ||.:.|..:.||..:...|.                   :.:...||.|.:....:|..:.....
  Fly    11 GHSDSVVELSFNRDYDTGYF-------------------LASAGLDGVAALRHGDTGDCITHLRK 56

  Fly   223 HTAELVAAEF-HPVDGKSIATASLDGSARIYDVETSHELQQLTHHGAEVIAARFNRDGQMLLTGS 286
            ||..:.:... |  |.|.:|:...|...|::|.....:|::| .|...|.....|.....||||.
  Fly    57 HTDSVWSVSLSH--DAKILASGGADCKVRVWDALLGKQLKKL-RHTKTVACVDLNPKATRLLTGC 118

  Fly   287 FDHSA--AIWDVR--SKSLGHQLRGHSAELSNCVWNFSGSLIATGSLDNTARIWDTRK------- 340
            .|..:  |::|:.  .|:...:.||||..:.:.::........:.|.|.|.|:||.|.
  Fly   119 IDQESPLALFDMEQSEKAPLMEFRGHSRGVRDVIFCLEEHCFLSSSYDRTVRMWDCRTGTRTNSI 183

  Fly   341 -LDQEL-YLAARHSDEVLDVSFDAAGQL-----------------------------LATCSSDC 374
             |...: .|...||.:::.::: |.|.:                             :..|.::
  Fly   184 FLPHHVKSLELHHSGDIVTIAY-AGGVIFLDPKSFEVLKHRKLPYKVTAASLSPNKGIYVCGNN- 246

  Fly   375 TARVWRLEGSSELEMLSLMAGHSDEVSKVCFSPSGCMLLTASADNTARLWLTESGQCSQVLAGH- 438
            ....::.:..::::....::.....|..:.|||.|.:....|.|.:..||.....|.|.|  ||
  Fly   247 MGYSFKYDYDTDVDRGLYVSQEPSAVLALSFSPDGEVCAIGSQDGSIILWQMNPKQASVV--GHL 309

  Fly   439 ----EGE 441
                :||
  Fly   310 KDEDDGE 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	66/332 (20%)
		WD40 repeat	122..158	CDD:293791	66/332 (20%)
		WD40	154..467	CDD:238121	66/332 (20%)
		WD40 repeat	189..222	CDD:293791	4/32 (13%)
		WD40 repeat	228..265	CDD:293791	9/37 (24%)
		WD40 repeat	270..306	CDD:293791	10/39 (26%)
		WD40 repeat	314..348	CDD:293791	8/42 (19%)
		WD40 repeat	355..393	CDD:293791	3/66 (5%)
		WD40 repeat	400..436	CDD:293791	12/35 (34%)
		WD40 repeat	442..466	CDD:293791	66/332 (20%)
CG10459	NP_610513.2	WD40	<10..322	CDD:225201	66/332 (20%)
		WD40	11..297	CDD:295369	58/309 (19%)
		WD40 repeat	61..97	CDD:293791	9/38 (24%)
		WD40 repeat	103..143	CDD:293791	9/39 (23%)
		WD40 repeat	148..185	CDD:293791	7/36 (19%)
		WD40 repeat	190..222	CDD:293791	5/32 (16%)
		WD40 repeat	229..264	CDD:293791	1/35 (3%)
		WD40 repeat	272..298	CDD:293791	9/25 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR44156
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100