DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7568 and pof11

DIOPT Version :9

Sequence 1:	NP_001263071.1	Gene:	CG7568 / 43482	FlyBaseID:	FBgn0039673	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_594559.1	Gene:	pof11 / 2541707	PomBaseID:	SPAC29E6.01	Length:	506	Species:	Schizosaccharomyces pombe

Alignment Length:	219	Identity:	65/219 - (29%)
Similarity:	113/219 - (51%)	Gaps:	21/219 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 DGQMLLTGSFDHSAAIWDVRSKSLGHQLRGHSAELSNCVWNFSGSLIATGSLDNTARIWD-TRKL 341
            |.:::::||.|.:.::|||.|:.:.::|.|||..:....:....:|:.:||.|:|..||| ..:.
pombe   230 DDEIMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSGSSDSTIIIWDWQNRR 294

  Fly   342 DQELYLAARHSDEVLDVSFDAAGQLLATCSSDCTARVWRLEGSSELE-MLSLMAGHSDEVSKVCF 405
            ..::|..  |:|.||.|.  .:...:.:.|.|.|||||||:.:|..| .:.::.||...|:.|.:
pombe   295 PLKVYFG--HTDNVLGVV--VSENYIISSSRDHTARVWRLDATSPAEACMHVLRGHLASVNSVQY 355

  Fly   406 SPSGCMLLTASADNTARLWLTESGQCSQVLAGHEGEVFSCAYSYAGDAILTASKDNSCRFWRXYD 470
            |....:::|||:|.|.|.|...:|.|.:::..|:..: :|| .|.|..|::.|.|.:.|.:. ..
pombe   356 SSKTGLIVTASSDRTLRTWDITTGHCIRIIHAHQRGI-ACA-QYNGKFIVSGSSDLTIRIFEASS 418

  Fly   471 W-------------YTVQLNDGSI 481
            .             .||:.||..|
pombe   419 GKLLRMLQGHEDLIRTVRFNDEKI 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	60/189 (32%)
		WD40 repeat	122..158	CDD:293791
		WD40	154..467	CDD:238121	60/190 (32%)
		WD40 repeat	189..222	CDD:293791
		WD40 repeat	228..265	CDD:293791
		WD40 repeat	270..306	CDD:293791	8/27 (30%)
		WD40 repeat	314..348	CDD:293791	9/34 (26%)
		WD40 repeat	355..393	CDD:293791	14/38 (37%)
		WD40 repeat	400..436	CDD:293791	12/35 (34%)
		WD40 repeat	442..466	CDD:293791	8/23 (35%)
pof11	NP_594559.1	F-box-like	77..119	CDD:289689
		WD40	<206..501	CDD:225201	65/219 (30%)
		WD40	222..496	CDD:238121	65/219 (30%)
		WD40 repeat	224..259	CDD:293791	9/28 (32%)
		WD40 repeat	265..301	CDD:293791	9/35 (26%)
		WD40 repeat	306..344	CDD:293791	14/39 (36%)
		WD40 repeat	351..386	CDD:293791	11/34 (32%)
		WD40 repeat	392..426	CDD:293791	8/35 (23%)
		WD40 repeat	432..466	CDD:293791	5/11 (45%)
		WD40 repeat	473..495	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R947
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030