DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7568 and sel-10

DIOPT Version :9

Sequence 1:NP_001263071.1 Gene:CG7568 / 43482 FlyBaseID:FBgn0039673 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_506421.1 Gene:sel-10 / 179878 WormBaseID:WBGene00004767 Length:587 Species:Caenorhabditis elegans


Alignment Length:377 Identity:101/377 - (26%)
Similarity:163/377 - (43%) Gaps:46/377 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    94 EKLQKKLR-EPVKKKFYLHKCHNSHILPLTNVSFDRSGERCLTGSYDRTCHVINTQTAQVEHILS 157
            :|::|... .|:.....| :.|..|::....:..|    ..:|||.|.|..|......:|.:.|.
 Worm   234 DKIEKNWNANPIMGSAVL-RGHEDHVITCMQIHDD----VLVTGSDDNTLKVWCIDKGEVMYTLV 293

  Fly   158 GHDNVVFSVGFNFPHWLVYLQSGGSGNNLTTFSIIFSDKIVTGSFDGTAKVWSATSGQSLCTFYG 222
            ||...|         |...:...|.             .||:||.|.|.||||...|..|.|..|
 Worm   294 GHTGGV---------WTSQISQCGR-------------YIVSGSTDRTVKVWSTVDGSLLHTLQG 336

  Fly   223 HTAELVAAEFHPVDGKSIATASLDGSARIYDVETSHELQQLTHHGAEVIAARFNRDGQMLLTGSF 287
            ||:   ......:.|..:.|.|.|.:.|::|||:...|..|..|.|.|...:|  ||..:::|.:
 Worm   337 HTS---TVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQF--DGTTVVSGGY 396

  Fly   288 DHSAAIWDVRSKSLGHQLRGHSAELSNCVWNFSGSLIATGSLDNTARIWD-TRKLDQE-LYLAAR 350
            |.:..||:..:......|.||:..:.:.::....|::.:||||.:.|:|| ||...|| :.|...
 Worm   397 DFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDFTRPEGQECVALLQG 461

  Fly   351 HSDEVLDVSFDAAGQLLATCSSDCTARVWRLEGSSELEMLSLMAGHSDEVSKVCFSPSGCMLLTA 415
            |:.  |.......|.:|.:|::|...|||.:...:.:.|||   ||...::.:.:.... |:.|:
 Worm   462 HTS--LTSGMQLRGNILVSCNADSHVRVWDIHEGTCVHMLS---GHRSAITSLQWFGRN-MVATS 520

  Fly   416 SADNTARLWLTESGQCSQVL-----AGHEGEVFSCAYSYAGDAILTASKDNS 462
            |.|.|.:||..|.|...:.|     .|:.|.::....:....|....|::|:
 Worm   521 SDDGTVKLWDIERGALIRDLVTLDSGGNGGCIWRLCSTSTMLACAVGSRNNT 572

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7568NP_001263071.1 WD40 93..466 CDD:225201 101/377 (27%)
WD40 repeat 122..158 CDD:293791 9/35 (26%)
WD40 154..467 CDD:238121 87/316 (28%)
WD40 repeat 189..222 CDD:293791 13/32 (41%)
WD40 repeat 228..265 CDD:293791 10/36 (28%)
WD40 repeat 270..306 CDD:293791 8/35 (23%)
WD40 repeat 314..348 CDD:293791 12/35 (34%)
WD40 repeat 355..393 CDD:293791 11/37 (30%)
WD40 repeat 400..436 CDD:293791 10/40 (25%)
WD40 repeat 442..466 CDD:293791 3/21 (14%)
sel-10NP_506421.1 F-box-like 124..167 CDD:289689
WD40 <243..532 CDD:225201 91/326 (28%)
WD40 248..530 CDD:238121 89/319 (28%)
WD40 repeat 259..294 CDD:293791 9/38 (24%)
WD40 repeat 300..336 CDD:293791 15/48 (31%)
WD40 repeat 341..375 CDD:293791 9/33 (27%)
WD40 repeat 382..415 CDD:293791 7/34 (21%)
WD40 repeat 421..460 CDD:293791 13/38 (34%)
WD40 repeat 468..500 CDD:293791 8/31 (26%)
WD40 495..>572 CDD:295369 19/80 (24%)
WD40 repeat 506..529 CDD:293791 5/23 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R947
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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