Protein Alignment CG7568 and fbxw7

DIOPT Version :9

• Sequence 1: NP_001263071.1
• Gene: CG7568 / 43482
• FlyBaseID: FBgn0039673
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: XP_004911205.1
• Gene: fbxw7 / 100145670
• XenbaseID: XB-GENE-1000486
• Length: 703
• Species: Xenopus tropicalis
• Alignment Length: 425
• Identity: 100/425 - (23%)
• Similarity: 181/425 - (42%)
• Gaps: 97/425 - (22%)

  Fly    47 DRILLQTLAEAEEEQSPADLEKSPPPRPVSGSVARSQNAFSALKQALEKLQKKLREPVKKKFYLH 111
            |.:|.:...:.:....|..|:|....:|   ....|....:.::|  .::....|....|...:.
 Frog   313 DNLLWREKCKEDGIDEPLHLKKRKISKP---GFTHSPWKSAYIRQ--HRIDTNWRRGELKSPKVL 372

  Fly   112 KCHNSHILPLTNVSFDRSGERCLTGSYDRTCHVINTQTAQVEHILSGHDNVVFSVGFNFPHWLVY 176
            |.|:.|:  :|.:.|  .|.|.::||.|.|..|.:..|.:....|.||...|:|
 Frog   373 KGHDDHV--ITCLQF--CGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWS----------- 422

  Fly   177 LQSGGSGNNLTTFSIIFSDKIVTGSFDGTAKVWSATSGQSLCTFYGHTAELVAAEFHPVDGKSIA 241
                         |.:..:.|::||.|.|.|||:|.:|:.:.|.||||:.:.....|.   |.:.
 Frog   423 -------------SQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHE---KRVV 471

  Fly   242 TASLDGSARIYDVETSHELQQLTHHGAEVIAARFNRDGQMLLTGSFDHSAAIWDVRSKSLGHQLR 306
            :.|.|.:.|::|:||...|..|..|.|.|...::  ||:.:::|::|....:||..:::..|.|:
 Frog   472 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQ 534

  Fly   307 GHSAELSNCVWN--FSGSLIATGSLDNTARIWDTRKLDQELYLAARHSDEVLDVSFDAAGQLLAT 369
            ||    :|.|::  |.|..:.:||||.:.|:||..
 Frog   535 GH----TNRVYSLQFDGIHVVSGSLDTSIRVWDVE------------------------------ 565

  Fly   370 CSSDCTARVWRLEGSSELEMLSLMAGHSDEVSKVCFSPSGCMLLTASADNTARLWLTESGQCSQV 434
             :.:|               :..:.||....|.:....:  :|::.:||:|.::|..::|||.|.
 Frog   566 -TGNC---------------IHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQT 612

  Fly   435 LAG---HEGEVFSCAYSYAGDAILTASKDNSCRFW 466
            |.|   |:..| :| ..:..:.::|:|.|.:.:.|
 Frog   613 LQGPNKHQSAV-TC-LQFNKNFVITSSDDGTVKLW 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	91/377 (24%)
		WD40 repeat	122..158	CDD:293791	11/35 (31%)
		WD40	154..467	CDD:238121	77/318 (24%)
		WD40 repeat	189..222	CDD:293791	12/32 (38%)
		WD40 repeat	228..265	CDD:293791	10/36 (28%)
		WD40 repeat	270..306	CDD:293791	8/35 (23%)
		WD40 repeat	314..348	CDD:293791	11/35 (31%)
		WD40 repeat	355..393	CDD:293791	1/37 (3%)
		WD40 repeat	400..436	CDD:293791	10/35 (29%)
		WD40 repeat	442..466	CDD:293791	5/23 (22%)
fbxw7	XP_004911205.1	F-box-like	277..321	CDD:372399	2/7 (29%)
		WD40	370..646	CDD:238121	90/363 (25%)
		WD40 repeat	380..415	CDD:293791	11/36 (31%)
		WD40 repeat	421..455	CDD:293791	13/57 (23%)
		WD40 repeat	460..494	CDD:293791	9/36 (25%)
		WD40 repeat	501..534	CDD:293791	7/34 (21%)
		WD40 repeat	540..574	CDD:293791	11/79 (14%)
		WD40 repeat	582..614	CDD:293791	9/33 (27%)
		WD40 repeat	623..645	CDD:293791	5/23 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R947
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.030