DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alph and Pptc7

DIOPT Version :9

Sequence 1:	NP_651701.1	Gene:	alph / 43481	FlyBaseID:	FBgn0086361	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_796216.2	Gene:	Pptc7 / 320717	MGIID:	2444593	Length:	310	Species:	Mus musculus

Alignment Length:	204	Identity:	37/204 - (18%)
Similarity:	73/204 - (35%)	Gaps:	59/204 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GLGDALPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDHVKGIRTGFLRIDEVMRELP 109
            |:.|.:..|..:.|........:...|     |.::....|:..:.|..:.|.:..:  :..::|
Mouse    81 GVADGVGGWRDYGVDPSQFSGTLMRTC-----ERLVKEGRFVPSNPVGILTTSYCEL--LQNKVP 138

  Fly   110 EFTRESEKCGGTTAVCAFV---GLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYN 171
            ..        |::..|..|   ...:::.||.|||..::.|.|..|     |:   .:|::..:|
Mouse   139 LL--------GSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVV-----HR---SDEQQHYFN 187

  Fly   172 AGGSVMIKRVNGTLAVSRALGDYDFKNVKEKGQCEQLVSPEPEIFCQSRQDSDEF-------LVL 229
            ....:       ::|...|.|              .::|..|:     ..||..|       ::.
Mouse   188 TPFQL-------SIAPPEAEG--------------VVLSDSPD-----AADSTSFDVQLGDIILT 226

  Fly   230 ACDGIWDVM 238
            |.||::|.|
Mouse   227 ATDGLFDNM 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	37/204 (18%)
alph	NP_651701.1	PP2C_C	278..352	CDD:285117
Pptc7	NP_796216.2	PP2Cc	66..302	CDD:381813	37/204 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900