Protein Alignment alph and Ppm1k

DIOPT Version :10

• Sequence 1: NP_651701.1
• Gene: alph / 43481
• FlyBaseID: FBgn0086361
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001101333.1
• Gene: Ppm1k / 312381
• RGDID: 1308501
• Length: 372
• Species: Rattus norvegicus
• Alignment Length: 289
• Identity: 88/289 - (30%)
• Similarity: 140/289 - (48%)
• Gaps: 42/289 - (14%)

  Fly     8 PKTAKHNDEGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDALPDWSFFAVFDGHAGCKVSEHCA 72
            ||.:..|         .|.:|:.|.|.|.||    |.|......:..:|||:|||.|...::.|.
  Rat    88 PKISLEN---------VGCASLIGKRKENED----RFGFAQLTEEVLYFAVYDGHGGPAAADFCH 139

  Fly    73 KHL---LESIISTEEFIGGDHVKGIRTGFLRIDEVMRELPEFTRE-SEKCGGTTAVCAFV--GLT 131
            .|:   :..::..|:    |....:...||.||:........:.: |....||||..|.:  |:
  Rat   140 THMEKCVTDLLPREK----DLETVLTLAFLEIDKAFSSYAHLSADASLLTSGTTATVALLRDGV- 199

  Fly   132 QVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGG-----SVMIKRVNGTLAVSRAL 191
            ::.:|:.|||||:|||:|.|:..|.||.|...:|||||...||     |:....|||.||::|::
  Rat   200 ELVVASVGDSRALLCRKGKPMKLTTDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSI 264

  Fly   192 GDYDFKNVKEKGQCEQLVSPEPEIF-CQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMRVTS 255
            ||.|   :|..|     |..|||.. .:.....|.||||..|||..:::::::|.|::.    ..
  Rat   265 GDLD---LKASG-----VIAEPETTRIKLYHADDSFLVLTTDGINFMVNSQEICDFVNQ----CH 317

  Fly   256 NLVSIANQVVDTCLHKGSRDNMSIIIIAF 284
            :....|:.|.:..:..|:.||.:.:::.|
  Rat   318 DPKEAAHAVTEQAIQYGTEDNSTAVVVPF 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	84/271 (31%)
		PP2C_C	278..355	CDD:429684	1/7 (14%)
Ppm1k	NP_001101333.1	Critical for association with the BCKDH complex. /evidence=ECO:0000250|UniProtKB:Q8N3J5	46..61
		PP2Cc	95..346	CDD:238083	84/271 (31%)