DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alph and Ppm1d

DIOPT Version :9

Sequence 1:	NP_651701.1	Gene:	alph / 43481	FlyBaseID:	FBgn0086361	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_001099295.2	Gene:	Ppm1d / 287585	RGDID:	1305460	Length:	598	Species:	Rattus norvegicus

Alignment Length:	461	Identity:	123/461 - (26%)
Similarity:	169/461 - (36%)	Gaps:	141/461 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GVS--SMQGWRSEMED----------------AYYARAGLG---------------------DAL 50
            |||  |.||.|..|||                |...|..||                     |..
  Rat     8 GVSVFSDQGGRKYMEDVTQIVVEPEPAAEDKPAPVPRRALGLPATPSLVGVGPSGKGPAAARDPA 72

  Fly    51 PD----------------WSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDHVK---GIRT 96
            ||                .:||||.|||.|.:.::...:||...|...:.|...:..|   .||.
  Rat    73 PDAAASLPAGRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRK 137

  Fly    97 GFLRIDEVM----RELPEFTRESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCRQGVP------ 151
            |||.....|    .|.|:.........||||....:...::|:|:.|||..||..|..|
  Rat   138 GFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVR 202

  Fly   152 -VFATQDHKPILPEEKERIYNAGGSVMIKR-VNGT------------------------LAVSRA 190
             |..||||||.||:|:|||...|||||.|. ||..                        |||:||
  Rat   203 AVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHSGPVRRSTVIDQIPFLAVARA 267

  Fly   191 LGD---YDFKNVKEKGQCEQLVSPEPEIFCQSRQ-DSDEFLVLACDGIWDVMSNEDVCSFI---- 247
            |||   |||.:.|      .:|||||:....:.. ...::::|..||:|:::..:|..|..
  Rat   268 LGDLWSYDFFSGK------FVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMVPPQDAISMCQDQE 326

  Fly   248 HSRMRVTSNLVSIANQVVDTCLHKGSR-----DNMSIIIIAFPGAPKPTEEAIEAEHRLEKQIEK 307
            ..:..:.....|.|..:|:..|.:..:     ||.|.|:|..  :|:           ::.|...
  Rat   327 EKKYLMGEQGQSCAKMLVNRALGRWRQRMLRADNTSAIVICI--SPE-----------VDNQGNF 378

  Fly   308 ITRDEIESSKITD---YVDLLKCLQNRDDIEGLP-------PGGGLQSKYH----VIERTFKQEF 358
            ...||: ...:||   |.....|:.........|       |...|.||.|    |....|.::|
  Rat   379 TNEDEL-FLNLTDSPTYNSQETCVMTPSPSSTPPVKSLEEDPWPRLNSKDHIPALVRSNAFSEKF 442

  Fly   359 PDRPCE 364
            .:.|.|
  Rat   443 LEVPAE 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	104/365 (28%)
alph	NP_651701.1	PP2C_C	278..352	CDD:285117	18/87 (21%)
Ppm1d	NP_001099295.2	PP2C	84..361	CDD:278884	83/282 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810