DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alph and Ppm1a

DIOPT Version :9

Sequence 1:	NP_651701.1	Gene:	alph / 43481	FlyBaseID:	FBgn0086361	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	XP_038967714.1	Gene:	Ppm1a / 24666	RGDID:	3373	Length:	455	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	194/369 - (52%)
Similarity:	256/369 - (69%)	Gaps:	12/369 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGGFLDKPKTAKHNDEGEGNKLLFGVSSMQGWRSEMEDAYYARAGLGDALPDWSFFAVFDGHAGC 65
            ||.||||||..|||.:|:||.|.:|:|||||||.|||||:.|..||...|..||||||:|||||.
  Rat    74 MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYDGHAGS 138

  Fly    66 KVSEHCAKHLLESIISTEEFIGG------DHVK-GIRTGFLRIDEVMRELPEFTRESEKCGGTTA 123
            :|:::|.:|||:.|.:.::|.|.      ::|| |||||||.|||.||.:.|....::: .|:||
  Rat   139 QVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADR-SGSTA 202

  Fly   124 VCAFVGLTQVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNAGGSVMIKRVNGTLAVS 188
            |...:.....|..||||||.:|||.....|.||||||..|.|||||.||||||||:||||:||||
  Rat   203 VGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVS 267

  Fly   189 RALGDYDFKNVKEKGQCEQLVSPEPEIF-CQSRQDSDEFLVLACDGIWDVMSNEDVCSFIHSRMR 252
            |||||:|:|.|..||..|||||||||:. .:..::.|:|::||||||||||.||::|.|:.||:.
  Rat   268 RALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLE 332

  Fly   253 VTSNLVSIANQVVDTCLHKGSRDNMSIIIIAFPGAPKPTEEAIEAEHRLEKQIEKITRDEI--ES 315
            ||.:|..:.|:||||||:||||||||:|:|.||.|||.:.||::.|..|:|.:|....:.|  :.
  Rat   333 VTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSAEAVKKEAELDKYLENRVEEIIKKQG 397

  Fly   316 SKITDYVDLLKCLQNRDDIEGLPPGGGLQSKYHVIERTFKQEFP 359
            ..:.|.|.:::.|.: ::|..|||||.|.||.:|||..:.:..|
  Rat   398 EGVPDLVHVMRTLAS-ENIPSLPPGGELASKRNVIEAVYNRLNP 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	151/267 (57%)
alph	NP_651701.1	PP2C_C	278..352	CDD:285117	29/75 (39%)
Ppm1a	XP_038967714.1	PP2Cc	96..364	CDD:238083	151/268 (56%)
Ppm1a	XP_038967714.1	PP2C_C	358..436	CDD:400262	30/78 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	314	1.000	Domainoid score	I1251
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	396	1.000	Inparanoid score	I1894
OMA	1	1.010	-	-		QHG53745
OrthoDB	1	1.010	-	-		D262211at33208
OrthoFinder	1	1.000	-	-		FOG0000692
OrthoInspector	1	1.000	-	-		mtm9125
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	1	1.100	-	-	O	PTHR47992
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X444
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980