DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alph and PPTC7

DIOPT Version :9

Sequence 1:	NP_651701.1	Gene:	alph / 43481	FlyBaseID:	FBgn0086361	Length:	374	Species:	Drosophila melanogaster
Sequence 2:	NP_644812.1	Gene:	PPTC7 / 160760	HGNCID:	30695	Length:	304	Species:	Homo sapiens

Alignment Length:	203	Identity:	37/203 - (18%)
Similarity:	74/203 - (36%)	Gaps:	57/203 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GLGDALPDWSFFAVFDGHAGCKVSEHCAKHLLESIISTEEFIGGDHVKGIRTGFLRIDEVMRELP 109
            |:.|.:..|..:.|........:...|     |.::....|:..:.:..:.|.:..:  :..::|
Human    75 GVADGVGGWRDYGVDPSQFSGTLMRTC-----ERLVKEGRFVPSNPIGILTTSYCEL--LQNKVP 132

  Fly   110 EFTRESEKCGGTTAVCAFVGLT--QVYIANCGDSRAVLCRQGVPVFATQDHKPILPEEKERIYNA 172
                   ..|.:||....:..|  :::.||.|||..::.|.|..|     |:   .:|::..:|.
Human   133 -------LLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVV-----HR---SDEQQHYFNT 182

  Fly   173 GGSVMIKRVNGTLAVSRALGDYDFKNVKEKGQCEQLVSPEPEIFCQSRQDSDEF-------LVLA 230
            ...:       ::|...|.|              .::|..|:     ..||..|       ::.|
Human   183 PFQL-------SIAPPEAEG--------------VVLSDSPD-----AADSTSFDVQLGDIILTA 221

  Fly   231 CDGIWDVM 238
            .||::|.|
Human   222 TDGLFDNM 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	37/203 (18%)
alph	NP_651701.1	PP2C_C	278..352	CDD:285117
PPTC7	NP_644812.1	PP2Cc	60..296	CDD:412173	37/203 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900