Protein Alignment alph and PP2D1

DIOPT Version :9

• Sequence 1: NP_651701.1
• Gene: alph / 43481
• FlyBaseID: FBgn0086361
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_001239586.1
• Gene: PP2D1 / 151649
• HGNCID: 28406
• Length: 630
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 83/439 - (18%)
• Similarity: 154/439 - (35%)
• Gaps: 142/439 - (32%)

  Fly    32 WRSEMEDAYYARAGLGDALPDWSFFAVFDGHAGCKVSEHCAKHL--------------------L 76
            |:::|.|.:...:..|:. |:..||.:||||.|...:|..:..|                    .
Human   181 WKADMNDKFTVVSNFGNK-PNVCFFGLFDGHHGASAAELTSMELPVLLLHQLSKFDPSYQMTTDE 244

  Fly    77 ESIIST------EEFIG------------------GDHVKGIRTGFLRIDEVM----RELPEFTR 113
            :.||::      ||:..                  .|..|.....|.|:|.::    :|:...
Human   245 QQIINSFYTVFREEYAAIEDLFSAINKTEAVRCEYEDTHKAFAKAFWRMDRLLGLGRKEVSRV-- 307

  Fly   114 ESEKCGGTTAVCAFV--------------------GLTQ--------------VYIANCGDSRAV 144
               :..|.:||...:                    ||.:              :::||.|:.:||
Human   308 ---QWSGCSAVTCILEGKPKSPYAHKNWKRKNTHDGLAESSPSQEMPKIISGILHVANTGNVQAV 369

  Fly   145 LCRQGVPVFATQDHKPILPEEKERIYNAGGSVMIKR----VNGTLAVSRALGDYDFKNVKEKGQC 205
            |||.|.....|::|......|:.||...|..:....    |.|.:..:|.||.:.  |:|.|
Human   370 LCRNGKGFCLTKEHTTRNTNERRRILQNGAVISSNEPYGLVEGQVKTTRGLGFHG--NLKLK--- 429

  Fly   206 EQLVSPEPEIFCQSRQDSDEFLVLACDGIWDVMSNEDVCSF----IHSRMRVTSNLVSIANQVVD 266
             :.:.|.|:.......|..:||::|.:|:|:|:..|:|.:.    .|........::...:....
Human   430 -KSIIPAPQTISVPIDDLCQFLIVATNGLWEVLDKEEVTALAMTTFHMYKETYCPIIPNKSPSKG 493

  Fly   267 TCLHKGSRDNM----SIIIIAFPGAPKPTEEAIEAEHRLEKQIEKIT---RDEIESSKITDYVDL 324
            ..|...|..|:    |.|.:.|             :::...::...|   ::.:..|..:.|
Human   494 PLLFSTSEPNLTKSQSNIHVLF-------------QYKSVSEVRVSTTNSKENLSDSNYSKY--- 542

  Fly   325 LKCLQNRDDIEGLPPGGGLQSKYHVIERTFK----QEFPDRPCEGNGIS 369
              |:.|.:::|..|           .|.|.:    ::..|||...|.::
Human   543 --CIYNPENVETFP-----------AETTHRKPCSEKVTDRPTSVNDVA 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	69/345 (20%)
		PP2C_C	278..352	CDD:285117	10/76 (13%)
PP2D1	NP_001239586.1	PP2Cc	181..466	CDD:238083	62/296 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	557..578		5/20 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144757
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740