Protein Alignment alph and PPM1M

DIOPT Version :10

• Sequence 1: NP_651701.1
• Gene: alph / 43481
• FlyBaseID: FBgn0086361
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_653242.3
• Gene: PPM1M / 132160
• HGNCID: 26506
• Length: 459
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 82/342 - (23%)
• Similarity: 131/342 - (38%)
• Gaps: 128/342 - (37%)

  Fly    55 FFAVFDGHAG-------CKVSEHCAKHLLESII-------------------STEEFIGGDHVKG 93
            ::|:||||.|       ......|.:..||:::                   |..:|:   ..||
Human   120 YWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGLVATQPPMHLNGRCICPSDPQFV---EEKG 181

  Fly    94 IR----------TGFLRIDEVM-RELPEFTRESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCR 147
            ||          :.|...|||: |||    ..|.:.||.||:.|.....::|:||.|||||:|.|
Human   182 IRAEDLVIGALESAFQECDEVIGREL----EASGQMGGCTALVAVSLQGKLYMANAGDSRAILVR 242

  Fly   148 QGVPVFATQDHKPI----LPE-EKERIY--------------------------NAGGSVMIK-- 179
            :       .:.:|:    .|| |::||.                          :.|..|:.:
Human   243 R-------DEIRPLSFEFTPETERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDH 300

  Fly   180 ---------------------------RVNGTLAVSRALGDYDFKNVKEKGQCEQLVSPEPEIFC 217
                                       |:.|||||||.|||:..:.:....|.:..:...|::..
Human   301 HMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTV 365

  Fly   218 ----QSRQDSDEFLVLACDGIWDVMSNEDVC----SFI-------HSRMRVTSNLVSIANQVVDT 267
                |.....|:.:|:|.||:|||:|||.|.    ||:       |...::...|:.......|:
Human   366 LDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDS 430

  Fly   268 CLHKG--SRDNMSIIII 282
            ...:|  |.|::|:.:|
Human   431 LTEEGQVSYDDVSVFVI 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	82/342 (24%)
		PP2C_C	278..355	CDD:429684	2/5 (40%)
PPM1M	NP_653242.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..64
		PP2Cc	118..449	CDD:238083	82/342 (24%)