Protein Alignment alph and PPM1M

DIOPT Version :9

• Sequence 1: NP_651701.1
• Gene: alph / 43481
• FlyBaseID: FBgn0086361
• Length: 374
• Species: Drosophila melanogaster
• Sequence 2: NP_653242.3
• Gene: PPM1M / 132160
• HGNCID: 26506
• Length: 459
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 82/342 - (23%)
• Similarity: 131/342 - (38%)
• Gaps: 128/342 - (37%)

  Fly    55 FFAVFDGHAG-------CKVSEHCAKHLLESII-------------------STEEFIGGDHVKG 93
            ::|:||||.|       ......|.:..||:::                   |..:|:   ..||
Human   120 YWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGLVATQPPMHLNGRCICPSDPQFV---EEKG 181

  Fly    94 IR----------TGFLRIDEVM-RELPEFTRESEKCGGTTAVCAFVGLTQVYIANCGDSRAVLCR 147
            ||          :.|...|||: |||    ..|.:.||.||:.|.....::|:||.|||||:|.|
Human   182 IRAEDLVIGALESAFQECDEVIGREL----EASGQMGGCTALVAVSLQGKLYMANAGDSRAILVR 242

  Fly   148 QGVPVFATQDHKPI----LPE-EKERIY--------------------------NAGGSVMIK-- 179
            :       .:.:|:    .|| |::||.                          :.|..|:.:
Human   243 R-------DEIRPLSFEFTPETERQRIQQLAFVYPELLAGEFTRLEFPRRLKGDDLGQKVLFRDH 300

  Fly   180 ---------------------------RVNGTLAVSRALGDYDFKNVKEKGQCEQLVSPEPEIFC 217
                                       |:.|||||||.|||:..:.:....|.:..:...|::..
Human   301 HMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTV 365

  Fly   218 ----QSRQDSDEFLVLACDGIWDVMSNEDVC----SFI-------HSRMRVTSNLVSIANQVVDT 267
                |.....|:.:|:|.||:|||:|||.|.    ||:       |...::...|:.......|:
Human   366 LDVDQLELQEDDVVVMATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDS 430

  Fly   268 CLHKG--SRDNMSIIII 282
            ...:|  |.|::|:.:|
Human   431 LTEEGQVSYDDVSVFVI 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alph	NP_651701.1	PP2Cc	24..284	CDD:238083	82/342 (24%)
		PP2C_C	278..352	CDD:285117	2/5 (40%)
PPM1M	NP_653242.3	PP2Cc	118..449	CDD:238083	82/342 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144737
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840