Protein Alignment Trc8 and rnf145

DIOPT Version :9

• Sequence 1: NP_996303.1
• Gene: Trc8 / 43476
• FlyBaseID: FBgn0039668
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_001072260.1
• Gene: rnf145 / 779713
• XenbaseID: XB-GENE-979193
• Length: 695
• Species: Xenopus tropicalis
• Alignment Length: 846
• Identity: 210/846 - (24%)
• Similarity: 361/846 - (42%)
• Gaps: 207/846 - (24%)

  Fly     1 MSVRTKVLGLVDVMMRVPPVMVIDEILKMDMGMQSWLYPDKDKASGALATPTEAPAVPSGQDPFT 65
            |..:.|:..:::|.:|||.:|::|.:.:.|:
 Frog     1 MGAKEKLEAMLNVALRVPSIMLLDVLYRWDV---------------------------------- 31

  Fly    66 SIKELFSHMTTSAQSVLEQSIEKASEAAKTHGMLSSGFNSLMNELSKDQTLADVLSTTTVKFVLC 130
                          |...:.|:::|            .|:  |.|.:.:.||  |:...|.::|.
 Frog    32 --------------SSFFKQIQRSS------------LNN--NPLFQYKYLA--LNMHYVGYILS 66

  Fly   131 VFAFLSAACIFMLWTRHLVMVYMFLTSLGLTFLSYWSN----VSALALTERSPSMVEDLMSLNTT 191
            |       .:..|..:||..:|::..:..|.:..:..:    .|.|......|..:|.|......
 Frog    67 V-------VLLTLPRQHLAKLYLYFVAALLLYAGHQISRDYVRSELESGYEGPMHIEPLSMNRFI 124

  Fly   192 RLLDSGGVVMSLAPHLMAQWFMGMLFAYIHLGPRFEHVQRSMPIIFASPILLAMLPLPAKVVQHL 256
            ..|....||.:|...:|....:.:..|:                         ||||.|:    |
 Frog   125 TALVGQLVVCTLCSCVMKTKQIWLFSAH-------------------------MLPLLAR----L 160

  Fly   257 PVVAVFTPIILTKITLMQSAME-----ASRTVY------NGYQYAMNFVSNFGLSALIENEWQRL 310
            .:|.:.|.:::.|..::.:.:|     ||..:.      :.|:.....|..:||.||..:.|.:|
 Frog   161 CLVPIETIVVINKFAMIFTGLEVLYFLASNLLVPFNLAKSAYRELAQVVEVYGLLALGMSLWNQL 225

  Fly   311 NVPNVLRVFWTIRLIQGGYALATTESDEPLDLMTATQKLL-------VDGCETMTAVLGMT---- 364
            .||.:..|||.:......|...:|. |:|    |:.::||       .:.|.|..::||:.
 Frog   226 VVPVLFMVFWLVLFALQIYTYFSTR-DQP----TSRERLLFLFLTSIAECCSTPYSLLGLVFTVS 285

  Fly   365 ----GVISMFCHYIGRGFQWYLLTYDDEEKSLGTVSAVLFYILALQTGLTSLSPDKRFIRLCRNL 425
                ||::: |.:..:|::.::   :|...:.|....|...|||:||||..|....|...|...|
 Frog   286 FVALGVLTL-CKFYLQGYRAFM---NDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIIL 346

  Fly   426 CLLMTALLHFLHNIVSPILMSLSAARNPSRKRHVRALSVCAFLVVLSVSLLYHLWSQQSISTWLL 490
            .:::.::|..:..|..||:::|.|:|:.|..:|.||:|:|.||:|....:.|.:.....:..|||
 Frog   347 FIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPSYMAYMICQFFHMDFWLL 411

  Fly   491 AVTAFSVEVVVKVLVSLATYTLFLLDARRQFFWEKLDDYLYYVRAFGNSVEF-------CFGILL 548
            .:.:.|:...::||.:|..|.||:::..|:...|.:||.:|||......:||       .:|:..
 Frog   412 IIISSSILTSLQVLGTLFIYVLFMIEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSE 476

  Fly   549 FINGAWILIFESAQNATGGGIRAIMMCIHAYFNIWCEARAGWSVFMKRRSAVHKISALPEATPAQ 613
            .:.|.|.:            :.::::.||:|:|:|..|:.||..|:.||.||:||.:||.||..|
 Frog   477 TVFGEWTV------------MGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPVATKEQ 529

  Fly   614 LQAFDDVCAICYQEMYSAKITRCRHFFHGVCLRKWLYVQDRCPLCH-EIMMYTDKA--------- 668
            |:..:|:|:||||:|.||.||.|.||||..||:||||||:.||||| ::...:.:|
 Frog   530 LEQHNDICSICYQDMNSAVITPCSHFFHPGCLKKWLYVQETCPLCHCQLKSLSQQATGESGSSTN 594

  Fly   669 ---DENAPEAEPAPAAQAE---QPMRIYPRDDANNAAAQRRSPERAPVEASEQAPATS---SSSA 724
               :::|......|.::||   :|:          ||...||       |.||.|...   |.|.
 Frog   595 PVSEQSATNPPLGPVSRAEVTTEPL----------AAVPTRS-------ALEQEPTMDIKVSGSV 642

  Fly   725 AATIGAEAVSAIVESAAAVGEARSLVSVASSSSATHRISASGSSDSSYMTASAQSPPPTATSAAA 789
            ...||.      :|:..:.|||.     .:|:....|:.|.|.::...:...|.  ||.....|.
 Frog   643 EKRIGE------LEAHFSQGEAN-----LNSNEVLQRLQAKGEANPEDLNVKAL--PPECEHCAE 694

  Fly   790 V 790
            :
 Frog   695 I 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trc8	NP_996303.1	TRC8_N	122..590	CDD:290425	118/504 (23%)
		zf-rbx1	<618..659	CDD:289448	27/40 (68%)
		zf-RING_2	619..659	CDD:290367	27/39 (69%)
rnf145	NP_001072260.1	TRC8_N	8..506	CDD:372682	134/618 (22%)
		RING-H2_RNF145	533..575	CDD:319598	27/41 (66%)
		rad18	537..>651	CDD:273165	46/136 (34%)
		RING-H2 finger (C3H2C3-type)	537..574	CDD:319598	25/36 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..610		3/24 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D302551at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920