DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Trc8 and chfr

DIOPT Version :9

Sequence 1:NP_996303.1 Gene:Trc8 / 43476 FlyBaseID:FBgn0039668 Length:809 Species:Drosophila melanogaster
Sequence 2:NP_001093485.1 Gene:chfr / 564271 ZFINID:ZDB-GENE-030131-3522 Length:637 Species:Danio rerio


Alignment Length:202 Identity:43/202 - (21%)
Similarity:62/202 - (30%) Gaps:60/202 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   621 CAICYQEMYSA-KITRCRHFFHGVCLRKWLYVQDRCPLCHEIMMYTDKADENAPEAEPAPAAQAE 684
            |.||...:|.. .:..|.|.|...|...|:.....||.|.   ...::..:|........|...:
Zfish   277 CIICQDLLYDCISVQPCMHTFCAACYSGWMERSSFCPTCR---CPVERIRKNHILNNLVEAYLLQ 338

  Fly   685 QPMRIYPRDDANNAAAQRR--------------SPERA--------------------PVEASEQ 715
            .|.:....||..:..|:.:              |.|.|                    |.....|
Zfish   339 HPEKCRTEDDLRSMDARNKITQDMLQPKVERSFSDEEASSDYLFELSDNDSDISDMSQPYMMCRQ 403

  Fly   716 APATSSSSAAATIGAEAVSAIVESAAAVGEARSLVSVASSSSATHRISASGSSDSSYMTASAQS- 779
            .|......::|.       .|.|||    ::.||...|....:|       ||||:  ||:.|. 
Zfish   404 CPGYRKELSSAL-------WICESA----QSESLAKTAGDGPST-------SSDST--TAAPQEF 448

  Fly   780 -PPPTAT 785
             .||.|:
Zfish   449 RCPPQAS 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Trc8NP_996303.1 TRC8_N 122..590 CDD:290425
zf-rbx1 <618..659 CDD:289448 11/38 (29%)
zf-RING_2 619..659 CDD:290367 11/38 (29%)
chfrNP_001093485.1 FHA 10..98 CDD:238017
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 120..172
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 193..267
RING 276..319 CDD:238093 12/44 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 428..447 8/27 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5243
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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