Protein Alignment Trc8 and rnf145b

DIOPT Version :9

• Sequence 1: NP_996303.1
• Gene: Trc8 / 43476
• FlyBaseID: FBgn0039668
• Length: 809
• Species: Drosophila melanogaster
• Sequence 2: NP_956057.1
• Gene: rnf145b / 327056
• ZFINID: ZDB-GENE-030131-5264
• Length: 685
• Species: Danio rerio
• Alignment Length: 816
• Identity: 192/816 - (23%)
• Similarity: 343/816 - (42%)
• Gaps: 190/816 - (23%)

  Fly     1 MSVRTKVLGLVDVMMRVPPVMVIDEILKMDMGMQSWLYPDKDKASGALATPTEAPAVPSGQDPFT 65
            |:::.::..:::|.:|:|.:|:::.:.:.|:
Zfish     1 MAMKARLESVLNVGLRIPSIMLLEVLYRWDV---------------------------------- 31

  Fly    66 SIKELFSHMTTSAQSVLEQSIEKASEAAKTHGMLSSGFNSLMNELSKDQTLADVLSTTTVKFVLC 130
                          |...|.|::               :||.|.        .|.....:...|.
Zfish    32 --------------SSFFQKIQR---------------SSLNNN--------PVFQYKYIALYLH 59

  Fly   131 VFAFLSAACIFMLWTRHLVMVYMFLTSLGLTFLSYWSN----VSALALTERSPSMVEDLMSLN-- 189
            ...::.:..:..|..:|||.:|:::.:..|.|..:..:    ...|......|..:|.| |:|
Zfish    60 YVGYILSLVLLTLPRQHLVQLYLYVLTALLLFAGHQLSRDYVRGELDSGYEGPLYLEPL-SMNRF 123

  Fly   190 TTRLLDSGGVVMSLAPHLMAQWFMGMLFAYIHLGPRFEHVQRSMPIIFASPILLAMLPLPAKVVQ 254
            ||.|:  |.||:......:.|.....||: .||                       |||.|:
Zfish   124 TTALI--GQVVVCTLCSCVMQTRQIWLFS-AHL-----------------------LPLVAR--- 159

  Fly   255 HLPVVAVFTPIILTKITLMQSAME-----ASRTV--YN----GYQYAMNFVSNFGLSALIENEWQ 308
             |.:|.:.|.:.:.:..::.:.:|     ||..:  ||    .|:..:..|..:||.||..:.|.
Zfish   160 -LCLVPLETIVFINRFAMIFTGLEVLYFIASNLLVPYNLAKTAYRELVQVVEVYGLLALGMSLWN 223

  Fly   309 RLNVPNVLRVFWTIRLIQGGYALATTESDEPLDLMTATQKLL-------VDGCETMTAVLGMT-- 364
            :|.:|.:...||.:......|...:|....|     :.::||       .:.|.|..::||:.
Zfish   224 QLVLPVLFMCFWLVLFALQIYTYFSTRDQPP-----SRERLLFLFLTSIAECCSTPYSLLGLVFT 283

  Fly   365 ------GVISMFCHYIGRGFQWYLLTYDDEEKSLGTVSAVLFYILALQTGLTSLSPDKRFIRLCR 423
                  ||::: |.:..:|::.::   :|.....|....:...|||:||||..|....|...|..
Zfish   284 VSFVALGVLTL-CKFYLQGYRAFM---NDNAMHRGMTEGITLLILAVQTGLIELQVIHRAFLLSI 344

  Fly   424 NLCLLMTALLHFLHNIVSPILMSLSAARNPSRKRHVRALSVCAFLVVLSVSLLYHLWSQQSISTW 488
            .|.:::.::|..:..|..||:::|.|:|:.|..:|.||:|:|.||:|....:.|.:.....:..|
Zfish   345 ILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFRMDFW 409

  Fly   489 LLAVTAFSVEVVVKVLVSLATYTLFLLDARRQFFWEKLDDYLYYVRAFGNSVEF-------CFGI 546
            ||.:.:.|:...::||.:|..|.||:::..|:...|.:|:.:|||......:||       .:|:
Zfish   410 LLIIISSSILTSLQVLGTLLIYVLFMVEEFRKAPVENMDEVIYYVNGTYRLLEFLVAVCVVAYGV 474

  Fly   547 LLFINGAWILIFESAQNATGGGIRAIMMCIHAYFNIWCEARAGWSVFMKRRSAVHKISALPEATP 611
            ...:.|.|.:            :.:.::.:|:|:|:|..|:.||..|:.||.|||||.::|.|:.
Zfish   475 SETLFGEWTV------------MGSTIILVHSYYNVWLRAQLGWQSFLLRRDAVHKIQSMPTAST 527

  Fly   612 AQLQAFDDVCAICYQEMYSAKITRCRHFFHGVCLRKWLYVQDRCPLCHEIMMYTDKADENAPEAE 676
            .|||..:|:|:||:|:|.||.||.|.||||..||:||||||:.|||||..:     ..:..|.:.
Zfish   528 LQLQQHNDICSICFQDMKSAVITPCSHFFHAACLKKWLYVQETCPLCHGQL-----KSQLQPTSS 587

  Fly   677 PAPAAQAEQPMRIYPRDDANNAAAQRRSPE-----RAPVEASEQAPATSSSSAAATIGAEAVSAI 736
            |....|........||:    ...::|.|:     ...:.|.|.     .:||...:|.:.:...
Zfish   588 PGTPTQGTPAANQNPRE----VEQEQRQPQVELNTEEGIRAEEM-----KTSAEQKLGMDLLPGS 643

  Fly   737 VESAAAVGEARSLVSVASSSSATHRISASGSSDSSY 772
            :.:     :.:....||..|:.|    ||......|
Zfish   644 LNT-----QPKECDLVAEGSAGT----ASNLKGDDY 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trc8	NP_996303.1	TRC8_N	122..590	CDD:290425	117/506 (23%)
		zf-rbx1	<618..659	CDD:289448	26/40 (65%)
		zf-RING_2	619..659	CDD:290367	26/39 (67%)
rnf145b	NP_956057.1	TRC8_N	8..506	CDD:290425	129/620 (21%)
		zf-RING_2	535..575	CDD:290367	26/39 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..685		19/107 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9282
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D302551at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820