DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Trc8 and Chfr

DIOPT Version :9

Sequence 1:	NP_996303.1	Gene:	Trc8 / 43476	FlyBaseID:	FBgn0039668	Length:	809	Species:	Drosophila melanogaster
Sequence 2:	XP_006249597.1	Gene:	Chfr / 288734	RGDID:	1306360	Length:	664	Species:	Rattus norvegicus

Alignment Length:	171	Identity:	33/171 - (19%)
Similarity:	52/171 - (30%)	Gaps:	62/171 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   621 CAICYQEMYS-AKITRCRHFFHGVCLRKWLYVQDRCPLCH------------------EIMMYTD 666
            |.||...::. ..:..|.|.|...|...|:.....||.|.                  .::.:.|
  Rat   303 CIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLLQHPD 367

  Fly   667 KA----DENAPEAEPAPAAQAEQP----------------MRIYPRDDANNAAAQ-----RRSPE 706
            |:    |..:.:|.........||                :.:...|..::..:|     |:.||
  Rat   368 KSRSEEDVRSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYIVCRQCPE 432

  Fly   707 ---------RAPVEASE---------QAPATSSSSAAATIG 729
                     ..||..||         :||:||:|...|..|
  Rat   433 YRRQAVQSLPCPVPESELGATQALGGEAPSTSASLTTAAPG 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trc8	NP_996303.1	TRC8_N	122..590	CDD:290425
		zf-rbx1	<618..659	CDD:289448	10/38 (26%)
		zf-RING_2	619..659	CDD:290367	10/38 (26%)
Chfr	XP_006249597.1	FHA	16..105	CDD:238017
		FHA	<27..140	CDD:224630
		RING	302..345	CDD:238093	11/41 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900